ID   Y1318_METJA             Reviewed;         602 AA.
AC   Q58714;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Uncharacterized protein MJ1318;
GN   OrderedLocusNames=MJ1318;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01122}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L77117; AAB99325.1; -; Genomic_DNA.
DR   PIR; E64464; E64464.
DR   AlphaFoldDB; Q58714; -.
DR   SMR; Q58714; -.
DR   STRING; 243232.MJ_1318; -.
DR   MEROPS; S16.A12; -.
DR   EnsemblBacteria; AAB99325; AAB99325; MJ_1318.
DR   KEGG; mja:MJ_1318; -.
DR   eggNOG; arCOG01937; Archaea.
DR   HOGENOM; CLU_027628_0_0_2; -.
DR   InParanoid; Q58714; -.
DR   OMA; VMMTGMI; -.
DR   PhylomeDB; Q58714; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006515; P:protein quality control for misfolded or incompletely synthesized proteins; IBA:GO_Central.
DR   Gene3D; 3.30.230.10; -; 1.
DR   InterPro; IPR008269; Lon_proteolytic.
DR   InterPro; IPR027065; Lon_Prtase.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10046; PTHR10046; 1.
DR   Pfam; PF05362; Lon_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..602
FT                   /note="Uncharacterized protein MJ1318"
FT                   /id="PRO_0000107273"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        577..597
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          25..210
FT                   /note="Lon proteolytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
FT   ACT_SITE        110
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
FT   ACT_SITE        153
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01122"
SQ   SEQUENCE   602 AA;  67257 MW;  A5FBE1C388160AA3 CRC64;
     MKTWRENMKK ILTLLLITFL LNSAFAVIIK APAVSLTDRG YVGVPINIQI NVTKGDGHVF
     MDTMPLTELD MQGSARIAAK VAGEVTGKDM SKYNVYITVR SDVPVVGGPS AGGTMTIGII
     CELMNWSLNK HVMMTGTINP DGSIGPVGGI LEKIEAAKKA NCTIMLIPKG QRYVEVEGNK
     VDAVEFGKKL GIKVIEVGSI YEAIPYFTNK KIIMKEYPEN PLIEEKYKDI MKELSENVLK
     TANEKYENLS KELSNSYVGY EYQKALLNEL TTSKSLLEKA NDEYLKNKYY SATCSAFNAL
     IKLETIEHTL KYLTGEEDVK TFLTEVQNKI SHDKEIVYSK NVTTNNFEEI LAGRIRIAEA
     EKLLDNAWKS YYLGNYDEAI KYGSFAKLRG DSAIWWVSLK ENDNNGKIIN EAKLKSLAQQ
     YLDNAETILT YVETLFPNLP TDDLENDLES AKEAYKDGDY LLTIAESIDT CVKAEIPLVI
     FGDIEYSKKY ARNKINLAEN LGITPISALG YYEYANSLND TISKIMYYKY SSYYAQMDID
     VIKELNKSIS ENISSEINIV TNENVNIEET TTKENNVGIM ISAIIGGLIG FAGGYLARRV
     SA