ID   Y1320_DICDI             Reviewed;         574 AA.
AC   Q55DH0; O96901;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=PI-PLC X domain-containing protein DDB_G0269228;
GN   ORFNames=DDB_G0269228;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=AX2;
RA   Becker M.;
RL   Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; U80927; AAD09227.1; -; Genomic_DNA.
DR   EMBL; AAFI02000005; EAL71964.1; -; Genomic_DNA.
DR   RefSeq; XP_646161.1; XM_641069.1.
DR   AlphaFoldDB; Q55DH0; -.
DR   PaxDb; Q55DH0; -.
DR   EnsemblProtists; EAL71964; EAL71964; DDB_G0269228.
DR   GeneID; 8617113; -.
DR   KEGG; ddi:DDB_G0269228; -.
DR   dictyBase; DDB_G0269228; -.
DR   eggNOG; KOG4306; Eukaryota.
DR   HOGENOM; CLU_475242_0_0_1; -.
DR   InParanoid; Q55DH0; -.
DR   PhylomeDB; Q55DH0; -.
DR   PRO; PR:Q55DH0; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IBA:GO_Central.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.190; -; 1.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   SUPFAM; SSF51695; SSF51695; 1.
DR   PROSITE; PS50007; PIPLC_X_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..574
FT                   /note="PI-PLC X domain-containing protein DDB_G0269228"
FT                   /id="PRO_0000371335"
FT   DOMAIN          270..449
FT                   /note="PI-PLC X-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00270"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        158
FT                   /note="L -> V (in Ref. 1; AAD09227)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   574 AA;  68306 MW;  74BC23A8E876DBC6 CRC64;
     MFSSIMFKKK PKQNLNENEI TSQSTTTTST LSDSKPSEKK IKDNKNDKFK INENDTIVEI
     EWESDIQQKY DLIALYDNDT NVIDDYIWHW KINDEYTYNN NNTNIIRDPN KNYYIKYWRI
     DDNNNGINHH HHYNHHHHIN NHHHNHIKTN HHSLPPNLHL SPLHNNNHHR HHSHQFPKVS
     INNVYKQIHN YKLKNHFIRQ QFQNNSTTNQ DTIKIKLSHF EERNLLKSVD YSGEMFKQYS
     NWMTNNWERI KDKMVRDLVL PGSHDAATYG IKSSSLRVPG DKVPSFIPNS IVSKWSKTQS
     GNIFKQLTMG YRYFDLRVAP YPVTGKLYIY HAMFSVPVSE VLDDIVKFIK NTNYYQQPNS
     SNNNDEKQQL QQQQQLFKKE IILLHWNHLG YLSIEQHQEL QLMIKSKLDG MLANRQLGNN
     VKVRELEFTP IINIYDDNGL KKRIINDDGK KSKQPFDSIQ NEPLFWYSNK SLVSNYDSNQ
     FHTSKDVISF LSREVTYNHK DRFWVAQCIL TIDSKKLLHI TTNSLLDWNH SEFPKFLKFF
     ENLEEKKVPT NIIMTDFCTH YPITDYAIRR NINE