ID   Y1320_NATPD             Reviewed;         317 AA.
AC   Q3ISY4;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein NP_1320A {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=NP_1320A;
OS   Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM
OS   8858 / NBRC 14720 / NCIMB 2260 / Gabara) (Halobacterium pharaonis).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Natronomonas.
OX   NCBI_TaxID=348780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB
RC   2260 / Gabara;
RX   PubMed=16169924; DOI=10.1101/gr.3952905;
RA   Falb M., Pfeiffer F., Palm P., Rodewald K., Hickmann V., Tittor J.,
RA   Oesterhelt D.;
RT   "Living with two extremes: conclusions from the genome sequence of
RT   Natronomonas pharaonis.";
RL   Genome Res. 15:1336-1343(2005).
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DR   EMBL; CR936257; CAI48751.1; -; Genomic_DNA.
DR   RefSeq; WP_011322386.1; NC_007426.1.
DR   AlphaFoldDB; Q3ISY4; -.
DR   SMR; Q3ISY4; -.
DR   STRING; 348780.NP_1320A; -.
DR   EnsemblBacteria; CAI48751; CAI48751; NP_1320A.
DR   GeneID; 3701114; -.
DR   KEGG; nph:NP_1320A; -.
DR   eggNOG; arCOG04152; Archaea.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   OMA; PGVVYFR; -.
DR   OrthoDB; 76134at2157; -.
DR   Proteomes; UP000002698; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..317
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   NP_1320A"
FT                   /id="PRO_0000259362"
FT   DOMAIN          132..189
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        143..162
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   317 AA;  35135 MW;  7131F4435D87E7B9 CRC64;
     MSRSALVGNI TAMLEDAGFT VSDRCAIRPK SFDIAARRGD DVLLLKVLAN IDAFDGYTGT
     EMRRLGEYLD ATPLVIGLRT RDEELKPGVV YFRHGVPVFS PDTAMDLFIE EVPPLIYAAP
     GGLYVNIDGD LLSDIRSQED MSLGKLANEL GVSRRTVSKY EDGMSASVEV AAELEEIFDR
     KLASPVEVLS GAEEVRDDVD EPEAPEADPD DAEIVTVLTR VGFEVHPTMQ APFKAVSEDE
     KRERKVLTGH SEFNRTAEKR ARIMSSVGHV TRTRSVYVVD STKRDSVDGT ALIEREEFER
     IHDSDELENL IRERAEG