ID   Y1321_PYRHO             Reviewed;         337 AA.
AC   O59045;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0252 protein PH1321;
GN   OrderedLocusNames=PH1321;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0252 family. {ECO:0000305}.
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DR   EMBL; BA000001; BAA30427.1; -; Genomic_DNA.
DR   PIR; C71003; C71003.
DR   RefSeq; WP_010885413.1; NC_000961.1.
DR   AlphaFoldDB; O59045; -.
DR   SMR; O59045; -.
DR   STRING; 70601.3257744; -.
DR   EnsemblBacteria; BAA30427; BAA30427; BAA30427.
DR   GeneID; 1443650; -.
DR   KEGG; pho:PH1321; -.
DR   eggNOG; arCOG07144; Archaea.
DR   OMA; VYIVHTV; -.
DR   OrthoDB; 62980at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007562; Transglutaminase-like_domain.
DR   Pfam; PF04473; DUF553; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..337
FT                   /note="UPF0252 protein PH1321"
FT                   /id="PRO_0000159561"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   337 AA;  40240 MW;  63F38D12BA6DA765 CRC64;
     MQEYKELIKE CAKELEGLMP EISQKLVNIA KINSPDRAFL EYLKVVEQVS LMKTERKQKN
     KALIILWRYG EALEKELYSD VKFFAKPLHK RIFRFVDWKI IGMLFLVFII LPAITSNLWS
     FRSEHYVLYL NENVDFPREL CNYRTSWLYD FRTSMVCVLK YGYGSINVTL RGNSWEKGVE
     AQRFISDMEY DFDRVKSPIT YIQTPKETLR YKKGVCSDFA LLVANILLDN NVSPVYIVHT
     VVRKEPSGGH AAAGIYVNGT LWILDWGSKP TKFQEYLENI DRIWEIREVR IYRITRDRIT
     LERIYKARLE DDRWRFLYSV IIMLGIFILK RREWWIM