ID   Y1322_DEIRA             Reviewed;         389 AA.
AC   Q9RUR0;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Putative sugar efflux transporter DR_1322;
GN   OrderedLocusNames=DR_1322;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
CC   -!- FUNCTION: Involved in the efflux of sugars. The physiological role may
CC       be the detoxification of non-metabolizable sugar analogs (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Set
CC       transporter family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000513; AAF10890.1; -; Genomic_DNA.
DR   PIR; F75411; F75411.
DR   RefSeq; NP_295046.1; NC_001263.1.
DR   RefSeq; WP_010887964.1; NZ_CP015081.1.
DR   AlphaFoldDB; Q9RUR0; -.
DR   SMR; Q9RUR0; -.
DR   STRING; 243230.DR_1322; -.
DR   EnsemblBacteria; AAF10890; AAF10890; DR_1322.
DR   KEGG; dra:DR_1322; -.
DR   PATRIC; fig|243230.17.peg.1517; -.
DR   eggNOG; COG2814; Bacteria.
DR   HOGENOM; CLU_055598_3_0_0; -.
DR   InParanoid; Q9RUR0; -.
DR   OMA; FGFTVMY; -.
DR   OrthoDB; 626204at2; -.
DR   Proteomes; UP000002524; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004750; Sugar_efflux.
DR   PANTHER; PTHR23535:SF2; PTHR23535:SF2; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..389
FT                   /note="Putative sugar efflux transporter DR_1322"
FT                   /id="PRO_0000209364"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   389 AA;  40939 MW;  10AC099546D2C320 CRC64;
     MPHALGLTLA VLLLGLATSL AGPFMSLFAV QQVGMTPLQL GLFLTFNALS AVLVSTRLGR
     WADRRSDRKP LVLLTLAAGV LAYLALSGVR SVYGVMATGV LLLAVSSAAF PQVFAFARSG
     FAQAPGDLPE KAVTVLRAVF SFAWVVGPGV GAAVLGRWSF SGVFLLAALC YALAGLPLLF
     IRPPAPAPAQ PNSAPSPLTQ ELGAPPAPPM GWVVAAFTLY GMAMHMGMVM FSLFVTETLH
     GTSAQVGFLV GLCALLEIPV MLLFVLSKRL PGVEWLIKAG LLLFVVHFAL IYLAQGMPLL
     IATQVLRAAV LAVMAGLGMT YFQQLMPGRF SAATTLYSNT SVVGSMLSGI VAGAWAQVFG
     YRPVFLLCAA LSLAAWGMML WATRRPKLA