ID   CAPSD_BPS13             Reviewed;         427 AA.
AC   P07931;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Capsid protein F;
DE   AltName: Full=F protein;
DE   AltName: Full=GPF;
GN   Name=F;
OS   Enterobacteria phage S13 (Bacteriophage S13).
OC   Viruses; Monodnaviria; Sangervirae; Phixviricota; Malgrandaviricetes;
OC   Petitvirales; Microviridae; Bullavirinae; Sinsheimervirus;
OC   unclassified Sinsheimervirus.
OX   NCBI_TaxID=10844;
OH   NCBI_TaxID=590; Salmonella.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3007293; DOI=10.1016/0378-1119(85)90050-2;
RA   Lau P.C.K., Spencer J.H.;
RT   "Nucleotide sequence and genome organization of bacteriophage S13 DNA.";
RL   Gene 40:273-284(1985).
CC   -!- FUNCTION: Assembles to form an icosahedral capsid with a T=1 symmetry,
CC       about 30 nm in diameter, and consisting of 60 capsid proteins F. Upon
CC       virus binding to host cell, one of the spikes dissociates from the
CC       capsid and the virus interacts with LPS through the exposed EF loops on
CC       the F proteins. After the genome had been ejected, the channel formed
CC       by the F proteins at the unique fivefold axis remains open.
CC       {ECO:0000250|UniProtKB:P03641}.
CC   -!- SUBUNIT: Pentamerizes and interacts with H protein, G and B pentamers
CC       to form 12S pre-assembly complex. By binding with protein D, induces
CC       joining of twelve 12S complex to form the procapsid. The procapsid has
CC       an external scaffold made of 240 copies of protein D, 60 copies of the
CC       internally located B protein, and contains 60 copies of each of the
CC       viral structural proteins F and G. Upon genome packaging, interacts
CC       with protein J. The mature virion is composed of 60 copies each of the
CC       F, G, and J proteins, and 12 copies of the H protein.
CC       {ECO:0000250|UniProtKB:P03641}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03641}.
CC   -!- SIMILARITY: Belongs to the microviridae F protein family.
CC       {ECO:0000305}.
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DR   EMBL; M14428; AAA32590.1; -; Genomic_DNA.
DR   PIR; JS0457; JS0457.
DR   SMR; P07931; -.
DR   Proteomes; UP000002129; Genome.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.169.10; -; 1.
DR   InterPro; IPR016184; Capsid/spike_ssDNA_virus.
DR   InterPro; IPR003514; Microviridae_protein_F.
DR   InterPro; IPR037002; Microviridae_protein_F_sf.
DR   Pfam; PF02305; Phage_F; 1.
DR   SUPFAM; SSF88645; SSF88645; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Reference proteome; T=1 icosahedral capsid protein;
KW   Viral genome ejection through host cell envelope;
KW   Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT   INIT_MET        1
FT                   /note="Removed; by host"
FT                   /evidence="ECO:0000250|UniProtKB:P03641"
FT   CHAIN           2..427
FT                   /note="Capsid protein F"
FT                   /id="PRO_0000164891"
SQ   SEQUENCE   427 AA;  48618 MW;  BBF8D5C10AC2F75A CRC64;
     MSNVQTGAER MPHDLSHLGF LAGQIGRLIT ISTTPVIAGD SFEMDAVGAL RLSPLRRGLA
     IDSTVDIFTF YVPHRHVYGE RWIKFMKDGV NATPLPTVNT TSYIDHAAFL GTINPDTNKI
     PKHLFQGYLN IYNNYFKAPW MPDRTEANPN ELNEDDARYG FRCCHLKNIW TAPLPPETEL
     SRRMTTSTTS IDIMGLQAAY ANLHTDQERD YFMQRYRDVI SSFGGKTSYD ADNRPLLVMR
     SNFWASGYDV DGTDQTSLGQ FSGRVQQTYK HSVPRFFVPE HGTMFTLALV RFPPTATKEI
     QYLNAKGALT YTDIAGDPAL YGNLPPREIS MKDVFRSGDS SKKFKIAEGQ WYRYAPSYVS
     PVYHLLEGFP FIQEPPSGDL QERVLIRHHD YDHCFQSVQL LQWNSQVKFN VTVYRNLPTT
     RDSIMTS