Y1327_ARATH
ID Y1327_ARATH Reviewed; 499 AA.
AC Q9ZVS8; F4I0U8;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Putative DUF21 domain-containing protein At1g03270;
DE AltName: Full=CBS domain-containing protein CBSDUF4;
GN Name=CBSDUF4; OrderedLocusNames=At1g03270; ORFNames=F15K9.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19400948; DOI=10.1186/1471-2164-10-200;
RA Kushwaha H.R., Singh A.K., Sopory S.K., Singla-Pareek S.L., Pareek A.;
RT "Genome wide expression analysis of CBS domain containing proteins in
RT Arabidopsis thaliana (L.) Heynh and Oryza sativa L. reveals their
RT developmental and stress regulation.";
RL BMC Genomics 10:200-200(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC72127.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005278; AAC72127.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27552.1; -; Genomic_DNA.
DR PIR; B86164; B86164.
DR RefSeq; NP_171826.2; NM_100209.3.
DR AlphaFoldDB; Q9ZVS8; -.
DR SMR; Q9ZVS8; -.
DR STRING; 3702.AT1G03270.1; -.
DR PaxDb; Q9ZVS8; -.
DR PRIDE; Q9ZVS8; -.
DR ProteomicsDB; 242505; -.
DR EnsemblPlants; AT1G03270.1; AT1G03270.1; AT1G03270.
DR GeneID; 838595; -.
DR Gramene; AT1G03270.1; AT1G03270.1; AT1G03270.
DR KEGG; ath:AT1G03270; -.
DR Araport; AT1G03270; -.
DR TAIR; locus:2014520; AT1G03270.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_0_0_1; -.
DR InParanoid; Q9ZVS8; -.
DR OMA; ACAIKIM; -.
DR OrthoDB; 1446644at2759; -.
DR PRO; PR:Q9ZVS8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZVS8; baseline and differential.
DR Genevisible; Q9ZVS8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; -; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; PTHR12064; 1.
DR Pfam; PF01595; DUF21; 1.
DR SUPFAM; SSF54631; SSF54631; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain; Glycoprotein; Membrane; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..499
FT /note="Putative DUF21 domain-containing protein At1g03270"
FT /id="PRO_0000411681"
FT TOPO_DOM 1..32
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 54..91
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 113..114
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 136..145
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 167..499
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT DOMAIN 29..211
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT DOMAIN 230..291
FT /note="CBS 1"
FT DOMAIN 295..359
FT /note="CBS 2"
FT DOMAIN 365..431
FT /note="CBS 3"
FT CARBOHYD 181
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 357
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 391
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 484
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 499 AA; 54662 MW; 5086AFCD67975D26 CRC64;
MVVLSTLALV RAAYSLNSFV FEAEDIRFGS PWWFVVVGVA CFLVLFAGIM SGLTLGLMSL
GLVELEILQQ SGSSAEKKQA AAILPVVKKQ HQLLVTLLLC NAAAMEALPI CLDKIFHPFV
AVLLSVTFVL AFGEIIPQAI CSRYGLAVGA NFLWLVRILM IICYPIAYPI GKVLDAVIGH
NDTLFRRAQL KALVSIHSQE AGKGGELTHE ETMIISGALD LSQKTAEEAM TPIESTFSLD
VNTKLDWETI GKILSRGHSR IPVYLGNPKN IIGLLLVKSL LTVRAETEAP VSSVSIRKIP
RVPSDMPLYD ILNEFQKGSS HMAAVVKVKD KDKKNNMQLL SNGETPKENM KFYQSSNLTA
PLLKHESHDV VVDIDKVPKH VKNRGRNFQQ NGTVTRDLPC LLEDNEDAEV IGIITLEDVF
EELLQAEIVD ETDVYIDVHK RVRVAAAAAA AVSSITRASP AEIQSKVGQT VKKLVGKEAR
GTKNYTTKIT EPLLAESDR
