ID   Y1333_NEIMB             Reviewed;         596 AA.
AC   Q9JZ20;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein NMB1333;
DE   Flags: Precursor;
GN   OrderedLocusNames=NMB1333;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17038831; DOI=10.4161/hv.1.2.1651;
RA   Vipond C., Wheeler J.X., Jones C., Feavers I.M., Suker J.;
RT   "Characterization of the protein content of a meningococcal outer membrane
RT   vesicle vaccine by polyacrylamide gel electrophoresis and mass
RT   spectrometry.";
RL   Hum. Vaccin. 1:80-84(2005).
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
CC   -!- SIMILARITY: Belongs to the peptidase M23B family. {ECO:0000305}.
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DR   EMBL; AE002098; AAF41708.1; -; Genomic_DNA.
DR   PIR; H81095; H81095.
DR   RefSeq; NP_274352.1; NC_003112.2.
DR   RefSeq; WP_002222357.1; NC_003112.2.
DR   AlphaFoldDB; Q9JZ20; -.
DR   SMR; Q9JZ20; -.
DR   STRING; 122586.NMB1333; -.
DR   PaxDb; Q9JZ20; -.
DR   PRIDE; Q9JZ20; -.
DR   EnsemblBacteria; AAF41708; AAF41708; NMB1333.
DR   KEGG; nme:NMB1333; -.
DR   PATRIC; fig|122586.8.peg.1672; -.
DR   HOGENOM; CLU_029425_4_0_4; -.
DR   OMA; WPATIRY; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR   GO; GO:0000920; P:septum digestion after cytokinesis; IBA:GO_Central.
DR   Gene3D; 2.70.70.10; -; 1.
DR   InterPro; IPR011055; Dup_hybrid_motif.
DR   InterPro; IPR016047; Peptidase_M23.
DR   Pfam; PF01551; Peptidase_M23; 1.
DR   SUPFAM; SSF51261; SSF51261; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..596
FT                   /note="Uncharacterized protein NMB1333"
FT                   /id="PRO_0000320334"
FT   REGION          25..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          177..281
FT                   /evidence="ECO:0000255"
FT   COILED          318..454
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        26..184
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   596 AA;  65741 MW;  5787ECC7FB6C42DB CRC64;
     MRYKPLLLAL MLVFSTPAVA AHDAAHNRSA EVKKQTKNKK EQPEAAEGKK EKGKNGAVKD
     KKTGGKEAAK EGKESKKTAK NRKEAEKEAT SRQSARKGRE GDKKSKAEHK KAHGKPVSGS
     KEKNAKTQPE NKQGKKEAKG QGNPRKGGKA EKDTVSANKK VRSDKNGKAV KQDKKYREEK
     NAKTDSDELK AAVAAATNDV ENKKALLKQS EGMLLHVSNS LKQLQEERIR QERIRQARGN
     LASVNRKQRE AWDKFQKLNT ELNRLKTEVA ATKAQISRFV SGNYKNSQPN AVALFLKNAE
     PGQKNRFLRY TRYVNASNRE VVKDLEKQQK ALAVQEQKIN NELARLKKIQ ANVQSLLKKQ
     GVTDAAEQTE SRRQNAKIAK DARKLLEQKG NEQQLNKLLS NLEKKKAEHR IQDAEAKRKL
     AEARLAAAEK ARKEAAQQKA EARRAEMSNL TAEDRNIQAP SVMGIGSADG FSRMQGRLKK
     PVDGVPTGLF GQNRSGGDIW KGVFYSTAPA TVESIAPGTV SYADELDGYG KVVVVDHGEN
     YISIYAGLSE ISVGKGYMVA AGSKIGSSGS LPDGEEGLYL QIRYQGQVLN PSSWIR