Y1337_MYCTU
ID Y1337_MYCTU Reviewed; 240 AA.
AC P9WM21; E2IBS6; F2GFD9; P64815; Q10647;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Uncharacterized protein Rv1337;
GN OrderedLocusNames=Rv1337; ORFNames=MTCY02B10.01, MTCY130.22;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BN44;
RX PubMed=21029479; DOI=10.1186/1471-2180-10-272;
RA Kateete D.P., Okee M., Katabazi F.A., Okeng A., Asiimwe J., Boom H.W.,
RA Eisenach K.D., Joloba M.L.;
RT "Rhomboid homologs in Mycobacteria: insights from phylogeny and genomic
RT analysis.";
RL BMC Microbiol. 10:272-272(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: To M.leprae ML1171. {ECO:0000305}.
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DR EMBL; HM453893; ADO17911.1; -; Genomic_DNA.
DR EMBL; AL123456; CCP44095.1; -; Genomic_DNA.
DR PIR; E70771; E70771.
DR RefSeq; NP_215853.1; NC_000962.3.
DR RefSeq; WP_003898831.1; NZ_NVQJ01000031.1.
DR AlphaFoldDB; P9WM21; -.
DR STRING; 83332.Rv1337; -.
DR PaxDb; P9WM21; -.
DR DNASU; 886870; -.
DR GeneID; 45425315; -.
DR GeneID; 886870; -.
DR KEGG; mtu:Rv1337; -.
DR TubercuList; Rv1337; -.
DR eggNOG; COG0705; Bacteria.
DR OMA; PSYHIGA; -.
DR PhylomeDB; P9WM21; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR Gene3D; 1.20.1540.10; -; 1.
DR InterPro; IPR022764; Peptidase_S54_rhomboid_dom.
DR InterPro; IPR035952; Rhomboid-like_sf.
DR Pfam; PF01694; Rhomboid; 1.
DR SUPFAM; SSF144091; SSF144091; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..240
FT /note="Uncharacterized protein Rv1337"
FT /id="PRO_0000103811"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 240 AA; 25703 MW; E43B682C8606CB69 CRC64;
MGMTPRRKRR GGAVQITRPT GRPRTPTTQT TKRPRWVVGG TTILTFVALL YLVELIDQLS
GSRLDVNGIR PLKTDGLWGV IFAPLLHANW HHLMANTIPL LVLGFLMTLA GLSRFVWATA
IIWILGGLGT WLIGNVGSSC GPTDHIGASG LIFGWLAFLL VFGLFVRKGW DIVIGLVVLF
VYGGILLGAM PVLGQCGGVS WQGHLSGAVA GVVAAYLLSA PERKARALKR AGARSGHPKL
