ID   Y1339_MYCTU             Reviewed;         273 AA.
AC   P9WGC1; L0T6K2; P66873; Q10648;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Uncharacterized protein Rv1339;
GN   OrderedLocusNames=Rv1339; ORFNames=MTCY02B10.03, MTCY130.24;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION AS A DRUG TARGET [LARGE SCALE ANALYSIS].
RX   PubMed=19099550; DOI=10.1186/1752-0509-2-109;
RA   Raman K., Yeturu K., Chandra N.;
RT   "targetTB: a target identification pipeline for Mycobacterium tuberculosis
RT   through an interactome, reactome and genome-scale structural analysis.";
RL   BMC Syst. Biol. 2:109-109(2008).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- MISCELLANEOUS: Was identified as a high-confidence drug target.
CC   -!- SIMILARITY: Belongs to the AtsA family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44097.1; -; Genomic_DNA.
DR   PIR; B70739; B70739.
DR   RefSeq; NP_215855.1; NC_000962.3.
DR   RefSeq; WP_003406922.1; NC_000962.3.
DR   AlphaFoldDB; P9WGC1; -.
DR   SMR; P9WGC1; -.
DR   STRING; 83332.Rv1339; -.
DR   PaxDb; P9WGC1; -.
DR   DNASU; 886972; -.
DR   GeneID; 886972; -.
DR   KEGG; mtu:Rv1339; -.
DR   PATRIC; fig|83332.111.peg.1494; -.
DR   TubercuList; Rv1339; -.
DR   eggNOG; COG1234; Bacteria.
DR   OMA; HIPPWTD; -.
DR   PhylomeDB; P9WGC1; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0042781; F:3'-tRNA processing endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0042779; P:tRNA 3'-trailer cleavage; IBA:GO_Central.
DR   Gene3D; 3.60.15.10; -; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..273
FT                   /note="Uncharacterized protein Rv1339"
FT                   /id="PRO_0000192688"
SQ   SEQUENCE   273 AA;  29154 MW;  7F555606A74C55F7 CRC64;
     MRRCIPHRCI GHGTVVSVRI TVLGCSGSVV GPDSPASGYL LRAPHTPPLV IDFGGGVLGA
     LQRHADPASV HVLLSHLHAD HCLDLPGLFV WRRYHPSRPS GKALLYGPSD TWSRLGAASS
     PYGGEIDDCS DIFDVHHWAD SEPVTLGALT IVPRLVAHPT ESFGLRITDP SGASLAYSGD
     TGICDQLVEL ARGVDVFLCE ASWTHSPKHP PDLHLSGTEA GMVAAQAGVR ELLLTHIPPW
     TSREDVISEA KAEFDGPVHA VVCDETFEVR RAG