ID   Y1343_STRP1             Reviewed;         494 AA.
AC   Q99Z89; Q48Y59;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=UPF0371 protein SPy_1343/M5005_Spy1095 {ECO:0000255|HAMAP-Rule:MF_01567};
GN   OrderedLocusNames=SPy_1343, M5005_Spy1095;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SIMILARITY: Belongs to the UPF0371 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01567}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK34174.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAZ51713.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE004092; AAK34174.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP000017; AAZ51713.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_269453.1; NC_002737.2.
DR   AlphaFoldDB; Q99Z89; -.
DR   SMR; Q99Z89; -.
DR   PaxDb; Q99Z89; -.
DR   EnsemblBacteria; AAK34174; AAK34174; SPy_1343.
DR   KEGG; spy:SPy_1343; -.
DR   KEGG; spz:M5005_Spy1095; -.
DR   PATRIC; fig|160490.10.peg.1173; -.
DR   HOGENOM; CLU_046981_0_0_9; -.
DR   OMA; HPVNIAY; -.
DR   Proteomes; UP000000750; Chromosome.
DR   HAMAP; MF_01567; UPF0371; 1.
DR   InterPro; IPR014999; UPF0371.
DR   Pfam; PF08903; DUF1846; 1.
DR   PIRSF; PIRSF033132; DUF1846; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..494
FT                   /note="UPF0371 protein SPy_1343/M5005_Spy1095"
FT                   /id="PRO_0000245620"
SQ   SEQUENCE   494 AA;  55359 MW;  52A1A1080828ED8B CRC64;
     MKTIAFDSNK YLNLQRDHIL ERISQFDGKL YMEFGGKMLE DYHAARVLPG YEPDNKIKLL
     KELKEQVEIV IAINANNIEH SKARGDLGIS YDQEVFRLID KFNTLDIYVG SVVITQYNNQ
     PAADAFRKQL EKNGIASYLH YPIKGYPTDI NHIISSEGMG KNNYIKTSRN LIVVTAPGPG
     SGKLATCMSQ MYHDQINGVK SGYAKFETFP VWNLPLHHPV NLAYEAATAD LDDVNMIDPF
     HLETYGKTAV NYNRDIEVFP VLNRTFERIL SKSPYASPTD MGVNMVGFSI VNEEAAIEAS
     KQEIIRRYYQ TLVDFKAERV TESAVKKIEL LMNDIGVTPD DRHVTVAAHQ KAEQTGQPAL
     ALQLPNGQIV TGKTSELFGP TAAVIINAIK TLAKIDKTTH LIEPEYVKPI QGLKVNHLGS
     HNPRLHSNEI LIALAITAMT SEEANLAMKE LGNLKGSEAH STVILTEEDK NVLRKLGVNI
     TFDPVYQHHK LYRK