ID   Y1344_MYCVP             Reviewed;         305 AA.
AC   A1T4S8;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mvan_1344;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mvan_1344;
OS   Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS   KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC   PYR-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Anderson I.J., Miller C., Richardson P.;
RT   "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000511; ABM12178.1; -; Genomic_DNA.
DR   RefSeq; WP_011778607.1; NC_008726.1.
DR   AlphaFoldDB; A1T4S8; -.
DR   SMR; A1T4S8; -.
DR   STRING; 350058.Mvan_1344; -.
DR   PRIDE; A1T4S8; -.
DR   EnsemblBacteria; ABM12178; ABM12178; Mvan_1344.
DR   KEGG; mva:Mvan_1344; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; FFIKMMD; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000009159; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..305
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mvan_1344"
FT                   /id="PRO_0000361258"
FT   BINDING         130
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         159..160
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   305 AA;  32738 MW;  E35EE65823707BA7 CRC64;
     MARTADDSWD PASSVGATAT MVAAGRAAAS ADPDPLINDP YAEPLVRAVG LSFFTKMLDG
     ELDLSQFADG SPERVQAMID GMAVRTRFFD DCCGTSTTAG ITQVVILASG LDARAYRLGW
     PAGTVVYELD QPAVIEFKTR TLAGLGAHPT ATHRPVPIDL REDWPAALHA AGFDASRPTA
     WLAEGLLIYL PPEAQDQLFD RITALSAPGS TIATEYAPGI IDFDDEKARA MSAPMREMGL
     DIDMPSLVYA GTRSHVMDYL AGQGWEVTGV PRRELFTRYG RPLPPEAGDT DPLGEIVYVS
     AHRPQ