ID   Y1345_MYCVP             Reviewed;         306 AA.
AC   A1T4S9;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mvan_1345;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mvan_1345;
OS   Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS   KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC   PYR-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Anderson I.J., Miller C., Richardson P.;
RT   "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000511; ABM12179.1; -; Genomic_DNA.
DR   RefSeq; WP_011778608.1; NC_008726.1.
DR   AlphaFoldDB; A1T4S9; -.
DR   SMR; A1T4S9; -.
DR   STRING; 350058.Mvan_1345; -.
DR   EnsemblBacteria; ABM12179; ABM12179; Mvan_1345.
DR   KEGG; mva:Mvan_1345; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; GMASRTW; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000009159; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..306
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mvan_1345"
FT                   /id="PRO_0000361259"
FT   BINDING         134
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         163..164
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   306 AA;  33054 MW;  DA1645903AA40A05 CRC64;
     MARTEGDTWD LGSSVGATAT SVAANRAFAS RSTAGGPEPL LNDPYADLLV EAVGLPHFIR
     VARGEIDFDD DPLFGARQML EQITVRTRHF DDFFAGAMAA GPPKIRQAVI LASGLDTRAY
     RLPWPAGTVV YEIDQPTVIE FKTAVLADAG VAPTAERRTV GIDLREDWPA ALRGAGFDPT
     RPTAWIAEGL LIYLPPDAQD RLLDHITALS APGSRLATEH MDAKALTGEW ARAMTERARR
     HGSDVNLSEL FYSGPRTSAT EHLRAQGWQT EVLSSNDAYQ AQGFAPVADH LVAMIGDSGY
     LTARLD