ID   Y1346_MYCVP             Reviewed;         310 AA.
AC   A1T4T0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase Mvan_1346;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Mvan_1346;
OS   Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS   KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC   PYR-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Anderson I.J., Miller C., Richardson P.;
RT   "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000511; ABM12180.1; -; Genomic_DNA.
DR   RefSeq; WP_011778609.1; NC_008726.1.
DR   AlphaFoldDB; A1T4T0; -.
DR   SMR; A1T4T0; -.
DR   STRING; 350058.Mvan_1346; -.
DR   EnsemblBacteria; ABM12180; ABM12180; Mvan_1346.
DR   KEGG; mva:Mvan_1346; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; DFFTRWV; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000009159; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..310
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase Mvan_1346"
FT                   /id="PRO_0000361260"
FT   BINDING         136
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         165..166
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   310 AA;  33727 MW;  D70CCB0E903F383F CRC64;
     MARTDNDTWD LASSVGATAT MVAAARAVAT RAPRPVIDDP FAAPLVQAVG VDFFTRLATG
     ELTTEELDTN DAESPVGMSR FADAMAARTR FFDDFFAEAM RAGPPPIRQG VILASGLDAR
     AYRLSWPQDM VLFEIDQPEV LTFKAATLAD LGVRPSTKLA TVAVDLRNDW PAALAEAGFD
     ASAPTAWIAE GLLGYLPPDA QDRLLDTIGE LSAPGSRLAV ESVPTHHEAD QEELREKMKE
     SSDRWRSHGF DVDFSELVFL GERADVTDYL RDRGWTVDAT PTNQLLTRYG LAPLDSDEGF
     AEVVYVSATR