ID   Y1349_AQUAE             Reviewed;         268 AA.
AC   O67364;
DT   11-JUL-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=UPF0719 transmembrane protein aq_1349;
GN   OrderedLocusNames=aq_1349;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0719 family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC07335.1; -; Genomic_DNA.
DR   PIR; A70417; A70417.
DR   RefSeq; NP_213928.1; NC_000918.1.
DR   RefSeq; WP_010880866.1; NC_000918.1.
DR   AlphaFoldDB; O67364; -.
DR   STRING; 224324.aq_1349; -.
DR   EnsemblBacteria; AAC07335; AAC07335; aq_1349.
DR   KEGG; aae:aq_1349; -.
DR   eggNOG; COG3766; Bacteria.
DR   HOGENOM; CLU_1036841_0_0_0; -.
DR   OrthoDB; 1293024at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007140; DUF350.
DR   Pfam; PF03994; DUF350; 3.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..268
FT                   /note="UPF0719 transmembrane protein aq_1349"
FT                   /id="PRO_0000186922"
FT   TRANSMEM        5..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   268 AA;  30387 MW;  B3EA0501514FFAA3 CRC64;
     MSGFLIALFW VIFSKYVFDV LFFREAKIER EIFGNKNLAL SLSYAGYFLG LAFSFYSVYF
     YESLFREVLY LIFVSFTLLL GVYIFDLIFL RKIDLKEEIL RGNAGAGITQ GIYFLSLGIL
     ISASFWRKES FILSVIYSLI YLSLGMVMLF ISTLLMSRLL KLNFEEEVKK ENFSASLVLG
     SITLGVSVVL YGAISGEFMG SLIFDLFSTV LYFVVSQVLM VIFYVVVEFL LFRKVILSSE
     VYENNLSASL ILSATFIASA FITLAVMG