ID   Y134_TREPA              Reviewed;         376 AA.
AC   O83170;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Uncharacterized lipoprotein TP_0134;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0134;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TP013X lipoprotein family. {ECO:0000305}.
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DR   EMBL; AE000520; AAC65125.1; -; Genomic_DNA.
DR   PIR; C71363; C71363.
DR   RefSeq; WP_010881582.1; NC_021490.2.
DR   AlphaFoldDB; O83170; -.
DR   IntAct; O83170; 3.
DR   STRING; 243276.TPANIC_0134; -.
DR   EnsemblBacteria; AAC65125; AAC65125; TP_0134.
DR   KEGG; tpa:TP_0134; -.
DR   eggNOG; ENOG5030DBM; Bacteria.
DR   HOGENOM; CLU_056007_0_0_12; -.
DR   OMA; TGWGTNC; -.
DR   OrthoDB; 1890188at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..376
FT                   /note="Uncharacterized lipoprotein TP_0134"
FT                   /id="PRO_0000018066"
FT   LIPID           29
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           29
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   376 AA;  40101 MW;  45155887C68283ED CRC64;
     MCKPRVWRIA HTIVHVGALL LGTSQLTTCD FSGIFATIQQ EVAIKSPSIP GAIYGLVKAG
     DKLYATNGRL WEKELNGIKW KPVPFLDGQD KRIDSLAASN TCVFACVSGD GVYKYTAGTT
     SSQKESNTDK AQAVVQMSDG KVVLQCALGD EKTTPSDADE RLLGGGQGYL VTSKGFYTLP
     GSASCEVISE TKDVTCKAEA PILASACDGS NTYILTKDKV YCRYTNGSGS TPTTWCDVEH
     KVSEPLALAV FKNKGETFLL VGGQQGYGEI KIATASGSSS SSSCVPLTAE NVHATTGWGA
     NCSTPEGSAE QYRSTIGRWA VSGIYVIKKD TSGGRKKRST STDCERPDLY VAVGDASDTY
     TGLWKFDTAT NTWNRE