ID   CAPSD_CAMVC             Reviewed;         488 AA.
AC   P03543;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Capsid protein;
DE            Short=CP;
DE   AltName: Full=Coat protein;
GN   ORFNames=ORF IV;
OS   Cauliflower mosaic virus (strain CM-1841) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10644;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6269062; DOI=10.1093/nar/9.12.2871;
RA   Gardner R.C., Howarth A.J., Hahn P., Brown-Luedi M., Shepherd R.J.,
RA   Messing J.;
RT   "The complete nucleotide sequence of an infectious clone of cauliflower
RT   mosaic virus by M13mp7 shotgun sequencing.";
RL   Nucleic Acids Res. 9:2871-2888(1981).
CC   -!- FUNCTION: Self assembles to form an icosahedral capsid, about 50 nm in
CC       diameter, nm, composed of 420 subunits of the viral capsid protein. The
CC       capsid encapsulates the genomic dsDNA. Following virus entry into host
CC       cell, provides nuclear import of the viral genome. Virus particles do
CC       not enter the nucleus, but dock at the nuclear membrane through the
CC       interaction with host importins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts (via nuclear localization signal) with host importin
CC       alpha. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the caulimoviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; V00140; CAA23455.1; -; Genomic_DNA.
DR   PIR; A04154; VCCV4C.
DR   Proteomes; UP000008438; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039620; C:T=7 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR   InterPro; IPR001988; Caulimo_coat.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PRINTS; PR00221; CAULIMOCOAT.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Metal-binding; Reference proteome;
KW   T=7 icosahedral capsid protein; Viral penetration into host nucleus;
KW   Virion; Virus entry into host cell; Zinc; Zinc-finger.
FT   CHAIN           1..488
FT                   /note="Capsid protein"
FT                   /id="PRO_0000222029"
FT   ZN_FING         410..427
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          80..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          463..488
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           121..124
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        91..130
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   488 AA;  56686 MW;  CF244DAA01378282 CRC64;
     MAESILDRTI NRFWYNLGED CLSESQFDLM IRLMEESLDG DQIIDLTSLP SDNLQVEQVM
     TTTDDSISEE SEFLLAIGEI SEDESDSGEE PEFEQVRMDR TGGTEIPKEE DGEGPSRYNE
     RKRKTPEDRY FPTQPKTIPG QKQTSMGMLN IDCQINRRTL IDDWAAEIGL IVKTNREDYL
     DPETILLLME HKTSGIAKEL IRNTRWNRTT GDIIEQVINA MYTMFLGLNY SDNKVAEKID
     EQEKAKIRMT KLQLFDICYL EEFTCDYEKN MYKTEMADFP GYINQYLSKI PIIGEKALTR
     FRHEANGTSI YSLGFAAKIV KEELSKICDL SKKQKKLKKF NKKCCSIGEA SVEYGGKKTS
     KKKYHKRYKK RYKVYKPYKK KKKFRSGKYF KPKEKKGSKR KYCPKGKKDC RCWICNIEGH
     YANECPNRQS SEKAHILQQA ENLGLQPVEE PYEGVQEVFI LEYKEEEEET STEESDDESS
     TSEDSDSD