ID   CAPSD_CAMVD             Reviewed;         490 AA.
AC   P03544;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Capsid protein;
DE            Short=CP;
DE   AltName: Full=Coat protein;
GN   ORFNames=ORF IV;
OS   Cauliflower mosaic virus (strain D/H) (CaMV).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Caulimoviridae; Caulimovirus.
OX   NCBI_TaxID=10645;
OH   NCBI_TaxID=3702; Arabidopsis thaliana (Mouse-ear cress).
OH   NCBI_TaxID=3705; Brassica.
OH   NCBI_TaxID=3725; Raphanus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7152260; DOI=10.1016/0378-1119(82)90013-0;
RA   Balazs E., Guilley H., Jonard G., Richards K.;
RT   "Nucleotide sequence of DNA from an altered-virulence isolate D/H of the
RT   cauliflower mosaic virus.";
RL   Gene 19:239-249(1982).
CC   -!- FUNCTION: Self assembles to form an icosahedral capsid, about 50 nm in
CC       diameter, nm, composed of 420 subunits of the viral capsid protein. The
CC       capsid encapsulates the genomic dsDNA. Following virus entry into host
CC       cell, provides nuclear import of the viral genome. Virus particles do
CC       not enter the nucleus, but dock at the nuclear membrane through the
CC       interaction with host importins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts (via nuclear localization signal) with host importin
CC       alpha. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the caulimoviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; M10376; AAA46348.1; -; Genomic_DNA.
DR   PIR; A04155; VCCV3.
DR   Proteomes; UP000008439; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039620; C:T=7 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR   InterPro; IPR001988; Caulimo_coat.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PRINTS; PR00221; CAULIMOCOAT.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Metal-binding;
KW   T=7 icosahedral capsid protein; Viral penetration into host nucleus;
KW   Virion; Virus entry into host cell; Zinc; Zinc-finger.
FT   CHAIN           1..490
FT                   /note="Capsid protein"
FT                   /id="PRO_0000222030"
FT   ZN_FING         411..428
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          79..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          464..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           122..125
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        92..131
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  56821 MW;  78DC9010D702E604 CRC64;
     MAESILDRTI NRFWYKLGDD CLSESQFDLM IRLMEESLDG DQIIDLTSLP SDNLQVEQVM
     TTTEDSISEE ESEFLLAIGE TSEEESDSGE EPEFEQVRMD RTGGTEIPKE EDGGEPSRYN
     ERKRKTTEDR YFPTQPKTIP GQKQTTMGML NIDCQANRRT LIDDWAAEIG LIVKTNREDY
     LDPETILLLM EHKTSGIAKE LIRNTRWNRT TGDIIEQVID AMYTMFLGLN YSDNKVAEKI
     EEQEKAKIRM TKLQLCDICY LEEFTCDYEK NMYKTELADF PGYINQYLSK IPIIGEKALT
     RFRHEANGTS IYSLGFAAKI VKEELSKICD LTKKQKKLKK FNKKCCSIGE ASVEYGCKKT
     SKKKYHKRYK KKYKAYKPYK KKKKFRSGKY FKPKEKKGSK QKYCPKGKKD CRCWICNIEG
     HYANECPNRQ SSEKAHILQQ AEKLGLQPIE EPYEGVQEVF ILEYKEEEEE TSTEEDDGSS
     TSEDSDSESD