Y1357_HALVD
ID Y1357_HALVD Reviewed; 582 AA.
AC D4GXP4; A0A384KM42; L9UTB8;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 18-MAY-2010, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Putative transcriptional regulator HVO_1357 {ECO:0000303|PubMed:33396553};
DE AltName: Full=Bacterioopsin activator-like protein {ECO:0000312|EMBL:ELY27957.1};
DE AltName: Full=Receiver/bat box HTH-10 family transcription regulator {ECO:0000312|EMBL:ADE03360.1};
GN OrderedLocusNames=HVO_1357 {ECO:0000312|EMBL:ADE03360.1};
GN ORFNames=C498_11958 {ECO:0000312|EMBL:ELY27957.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000312|EMBL:ADE03360.1};
RN [1] {ECO:0000312|EMBL:ADE03360.1, ECO:0000312|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC B-1768 / DS2 {ECO:0000312|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
RN [2] {ECO:0000312|EMBL:ELY27957.1, ECO:0000312|Proteomes:UP000011532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC B-1768 / DS2 {ECO:0000312|Proteomes:UP000011532};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
RN [3]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=DS2 / DS70 {ECO:0000303|PubMed:33396553};
RX PubMed=33396553; DOI=10.3390/genes12010058;
RA Collins M., Afolayan S., Igiraneza A.B., Schiller H., Krespan E.,
RA Beiting D.P., Dyall-Smith M., Pfeiffer F., Pohlschroder M.;
RT "Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax
RT volcanii, Suggesting Roles in Motility Regulation.";
RL Genes (Basel) 12:0-0(2020).
CC -!- FUNCTION: May be part of a signal-dependent gene regulation cascade
CC that is relevant to swimming motility. May be involved in the
CC transcription regulation of target genes.
CC {ECO:0000305|PubMed:33396553}.
CC -!- DISRUPTION PHENOTYPE: Cells having transposon insertions in this gene
CC are hypermotile. {ECO:0000269|PubMed:33396553}.
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DR EMBL; CP001956; ADE03360.1; -; Genomic_DNA.
DR EMBL; AOHU01000091; ELY27957.1; -; Genomic_DNA.
DR RefSeq; WP_004043582.1; NZ_AOHU01000091.1.
DR STRING; 309800.C498_11958; -.
DR EnsemblBacteria; ADE03360; ADE03360; HVO_1357.
DR EnsemblBacteria; ELY27957; ELY27957; C498_11958.
DR GeneID; 8926762; -.
DR KEGG; hvo:HVO_1357; -.
DR PATRIC; fig|309800.29.peg.2282; -.
DR eggNOG; arCOG02276; Archaea.
DR eggNOG; arCOG02601; Archaea.
DR HOGENOM; CLU_010057_2_0_2; -.
DR OMA; PATFNQH; -.
DR OrthoDB; 56183at2157; -.
DR Proteomes; UP000008243; Chromosome.
DR Proteomes; UP000011532; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:2000145; P:regulation of cell motility; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR013971; HalX_domain.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF08663; HalX; 1.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR SUPFAM; SSF88659; SSF88659; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Phosphoprotein; Reference proteome;
KW Transcription; Transcription regulation; Two-component regulatory system.
FT CHAIN 1..582
FT /note="Putative transcriptional regulator HVO_1357"
FT /id="PRO_0000454835"
FT DOMAIN 19..129
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 517..569
FT /note="HTH bat-type"
FT /evidence="ECO:0000255"
FT COILED 165..203
FT /evidence="ECO:0000255"
FT MOD_RES 67
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 582 AA; 62767 MW; 5A57DB8B0BA0ADD8 CRC64;
MVTERSARES PEQRAAEQVV LVVDDDEDLA DTCRYWLDGE RFAVETAYGG EEALHRLDDT
VDVVLLDRRM PNVTGDDVLE EIRERGLDCR VAMMTAVEPD TDIVEMPFDA YLVKPVSESE
VKETVEELLV RSGFESGVRE YFALESTEAA LDSRDVEELR EPEALSDLRS RLEAVRAEHE
AAIRNREAQL DRLNRTNELL RDVDRALIDA RTRDEIEQTV CDVVADAHEA AVVLRRTAAG
TLRCTAAAGH GLDPAGVDLD FVDEAFGVDG AAEDGFVFED IPGAHRAAVL GDDADDLDAV
SALCVSIDYR ETMYGALVVY DETDGFDDES AGLFSDLGAT VGNGINATQS KRLLNGDSVV
ELEFQVGRDA GVLARLSAAL DCQLSLDGVT RLDDGLACFI SVAGASGCDA VAAAIDAVDV
SQARVVADGD EESVVELRTD AEAVLSTAID HGASVERLTL SEGSGTLTLH VAADADHGAL
VEAVTTAAAG VSVVAKREVE RSVQSADSFR RALDSKLTDR QRTVLETSLV SGYFEWPRGS
TAEEVADSLG ISPPTLHEHL RTAERKLIET YFDELNQAPA DD
