ID   Y1360_MYCTU             Reviewed;         340 AA.
AC   P9WM03; L0T9E5; P64831; Q11030;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Uncharacterized protein Rv1360;
DE   Flags: Precursor;
GN   OrderedLocusNames=Rv1360; ORFNames=MTCY02B10.24;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION AS A DRUG TARGET [LARGE SCALE ANALYSIS].
RX   PubMed=19099550; DOI=10.1186/1752-0509-2-109;
RA   Raman K., Yeturu K., Chandra N.;
RT   "targetTB: a target identification pipeline for Mycobacterium tuberculosis
RT   through an interactome, reactome and genome-scale structural analysis.";
RL   BMC Syst. Biol. 2:109-109(2008).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- MISCELLANEOUS: Was identified as a high-confidence drug target.
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DR   EMBL; AL123456; CCP44118.1; -; Genomic_DNA.
DR   PIR; G70741; G70741.
DR   RefSeq; NP_215876.1; NC_000962.3.
DR   RefSeq; WP_003898842.1; NZ_NVQJ01000031.1.
DR   AlphaFoldDB; P9WM03; -.
DR   SMR; P9WM03; -.
DR   STRING; 83332.Rv1360; -.
DR   PaxDb; P9WM03; -.
DR   DNASU; 886813; -.
DR   GeneID; 45425340; -.
DR   GeneID; 886813; -.
DR   KEGG; mtu:Rv1360; -.
DR   TubercuList; Rv1360; -.
DR   eggNOG; COG2141; Bacteria.
DR   OMA; RMTEMCG; -.
DR   PhylomeDB; P9WM03; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 3.20.20.30; -; 1.
DR   InterPro; IPR019919; Lucif-like_OxRdtase_MSMEG_2256.
DR   InterPro; IPR011251; Luciferase-like_dom.
DR   InterPro; IPR036661; Luciferase-like_sf.
DR   Pfam; PF00296; Bac_luciferase; 1.
DR   SUPFAM; SSF51679; SSF51679; 1.
DR   TIGRFAMs; TIGR03617; F420_MSMEG_2256; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..340
FT                   /note="Uncharacterized protein Rv1360"
FT                   /id="PRO_0000014099"
SQ   SEQUENCE   340 AA;  37252 MW;  F4D3BCA7C5AC0767 CRC64;
     MGGARRLKLD GSIPNQLARA ADAAVALERN GFDGGWTAEA SHDPFLPLLL AAEHTSRLEL
     GTNIAVAFAR NPMIVANVGW DLQTYSKGRL ILGLGTQIRP HIEKRFSMPW GHPARRMREF
     VAALRAIWLA WQDGTKLCFE GEFYTHKIMT PMFTPEPQPY PVPRVFIAAV GEAMTEMCGE
     VADGHLGHPM VSKRYLTEVS VPALLRGLAR SGRDRSAFEV SCEVMVATGA DDAELAAACT
     ATRKQIAFYG STPAYRKVLE QHGWGDLHPE LHRLSKLGEW EAMGGLIDDE MLGAFAVVGP
     VDTIAGALRN RCEGVVDRVL PIFMAASQEC INAALQDFRR