Y1364_HAEIN
ID Y1364_HAEIN Reviewed; 288 AA.
AC P43011;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator HI_1364;
DE AltName: Full=ORF2;
GN OrderedLocusNames=HI_1364;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=8635745; DOI=10.1016/0378-1119(95)00777-6;
RA Chandler M.S., Smith R.A.;
RT "Characterization of the Haemophilus influenzae topA locus: DNA
RT topoisomerase I is required for genetic competence.";
RL Gene 169:25-31(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; U20964; AAC43726.1; -; Genomic_DNA.
DR EMBL; L42023; AAC23011.1; -; Genomic_DNA.
DR PIR; D64171; D64171.
DR RefSeq; NP_439515.1; NC_000907.1.
DR RefSeq; WP_010869193.1; NC_000907.1.
DR AlphaFoldDB; P43011; -.
DR SMR; P43011; -.
DR STRING; 71421.HI_1364; -.
DR PRIDE; P43011; -.
DR EnsemblBacteria; AAC23011; AAC23011; HI_1364.
DR KEGG; hin:HI_1364; -.
DR PATRIC; fig|71421.8.peg.1418; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_16_3_6; -.
DR OMA; VYPNRRH; -.
DR PhylomeDB; P43011; -.
DR BioCyc; HINF71421:G1GJ1-1389-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006351; P:transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..288
FT /note="Uncharacterized HTH-type transcriptional regulator
FT HI_1364"
FT /id="PRO_0000105798"
FT DOMAIN 1..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 19..38
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT CONFLICT 281..288
FT /note="VTGISLNF -> RAFIEFLSGLGLCSEIWENHEDNI (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 288 AA; 32423 MW; EEF3C22374352980 CRC64;
MDKLNAISIF CKVIETQSFT LAAKQQNISV AMASKLVSQL EEHLKTRLLQ RTTRKIMPTE
AGMMYYQRCQ GILLDLDEAD SSITQLTSSL QGNLLISVPR DFGLLFIAPN LPTFMAKHPH
LHIEVEFNDK KIDLLSEGYD LALRIGYMED SSLVSRKIGT TTVHFAASPN YLETNGIPQT
PDDLEHHNGL LYKNAMNQVN WVGSRINQTQ RFKIQSKVVS NSGFALLNMA KAGLGIANLP
KFILGRAFEK GELIEILPEY KQQKLEIHVV YPNRRHLPIK VTGISLNF
