ID   Y136_TREPA              Reviewed;         485 AA.
AC   O83172;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Uncharacterized lipoprotein TP_0136;
DE   Flags: Precursor;
GN   OrderedLocusNames=TP_0136;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TP013X lipoprotein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC65137.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000520; AAC65137.1; ALT_INIT; Genomic_DNA.
DR   PIR; B71360; B71360.
DR   AlphaFoldDB; O83172; -.
DR   IntAct; O83172; 3.
DR   STRING; 243276.TPANIC_0136; -.
DR   EnsemblBacteria; AAC65137; AAC65137; TP_0136.
DR   KEGG; tpa:TP_0136; -.
DR   HOGENOM; CLU_056007_0_0_12; -.
DR   OMA; HNGCEYL; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..485
FT                   /note="Uncharacterized lipoprotein TP_0136"
FT                   /id="PRO_0000018067"
FT   REGION          308..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           24
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           24
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   485 AA;  48984 MW;  C7A4CEEDC7DC5CED CRC64;
     MRRRVCTVVR AVVCLLSTSL LTTCDFTGIF AAIQSEVPIK TPSIPGAIYG LVKAGSKLYA
     TNGRLWEKEL NGTGSWQKVS SSSVPTDSDK KVMSIATDGN TFVLACVPGT GVYKHCVNGA
     GSSSTGTTAS PSTETCSQHA TLVGGTSKPF WLVPGGTGNN GNCGCGGGGG GSSSSSSSCI
     HIWLVPGGTG NNGNCGCGGG GGGSSSSSSS CIHIKVENTD EQFLDMGEGY VVTTKHLYTK
     NGSSSAGPAQ CPGGGGGGGS SGGGGSSEYT KASCSFSTPI LASVSDGCYH YILTKEKVYC
     RKQDTASSAA SSPAQCPSSP SSSSSSSTNA GCEVAHGVDD PLCLAIFKHN GCEYLLIGGS
     RGYGEIKLEA NSSGTNGTCM RLKESNVHKS PGQWGESSPT PKASAEQYRG TVGRFAVQKI
     YVVEKNGGGN GVAAGGAGCP ANASSSSGGT SSTQRPDLYA AVGESSDTYT GLWKFDTTTC
     SWNRE