ID   Y1371_ENTFA             Reviewed;         224 AA.
AC   Q835K6;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=UPF0173 metal-dependent hydrolase EF_1371 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=EF_1371;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE016830; AAO81162.1; -; Genomic_DNA.
DR   RefSeq; NP_815092.1; NC_004668.1.
DR   RefSeq; WP_002379405.1; NZ_KE136528.1.
DR   AlphaFoldDB; Q835K6; -.
DR   SMR; Q835K6; -.
DR   STRING; 226185.EF_1371; -.
DR   EnsemblBacteria; AAO81162; AAO81162; EF_1371.
DR   KEGG; efa:EF1371; -.
DR   PATRIC; fig|226185.45.peg.2129; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   OMA; WHGHSTW; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..224
FT                   /note="UPF0173 metal-dependent hydrolase EF_1371"
FT                   /id="PRO_0000367179"
SQ   SEQUENCE   224 AA;  24238 MW;  ADB4C4B5D6451B60 CRC64;
     MELIGHGHSC IEIRLNDGTN LLFDPFINGN PLADVSLADL HPDYILITHG HSDHIGDMLA
     IAQANKATII AIAEVAMYAQ SQGVKAHGMN LGGRYVFPFG SVKFVPALHS SGYEIDGVMT
     YMGEASGIIL EAEDKKIYHA GDTALFSDMR LFAKDKSIDV AFLPIGDNYT MGPEDALEAI
     AYLNPEITIP IHYNTFPVIQ QNPAIFVEQV VGGKVLNPGE TILV