ID   Y1374_SYNY3             Reviewed;         544 AA.
AC   P74168;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 130.
DE   RecName: Full=Uncharacterized symporter sll1374;
GN   OrderedLocusNames=sll1374;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA18257.1; -; Genomic_DNA.
DR   PIR; S75696; S75696.
DR   AlphaFoldDB; P74168; -.
DR   SMR; P74168; -.
DR   STRING; 1148.1653342; -.
DR   PaxDb; P74168; -.
DR   EnsemblBacteria; BAA18257; BAA18257; BAA18257.
DR   KEGG; syn:sll1374; -.
DR   eggNOG; COG2211; Bacteria.
DR   InParanoid; P74168; -.
DR   OMA; GLYTAWM; -.
DR   PhylomeDB; P74168; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR018043; Na/Gal_symport_CS.
DR   PANTHER; PTHR11328; PTHR11328; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..544
FT                   /note="Uncharacterized symporter sll1374"
FT                   /id="PRO_0000170773"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        501..521
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   544 AA;  60065 MW;  C91D0EDFF32277EE CRC64;
     MSQSLSAEKL HFTTKLAYGA GDFGPAITAN ILVFYLLFFL TDVAGIPAAL AGSVLMIGKI
     FDAINDPIIG LLSDRTRSRW GRRLPWMLGG MIPFALFYTA QWLIPHFSDD RLTNQWGLFI
     YYVAIAMAFN LCYTTVNLPY TALTPELTQN YNERTRLNSF RFAFSIGGSI LSLILYILIA
     AGLPDRPQQQ FGELGVMISV LSISALLWSA LRLQEKGKEP ILSPSLRRRL APLLMAAGIT
     LILLAIAKSF NLLGGSGFDY ISFFLILLGL IWGGFGFTLR DSAVEEHLQK LENSPSPGVT
     ENLPLLKQLK IAFSNRAFLF VIGIYLCSWL AVQLTASILV YFVVSWMGLN EQQSGTIALA
     VQGTALVMLF VWQALAQFLD KKVIYFLGSM VWMGAEAGLW LVQPGQVALL YTLAIFAGVG
     VSVAYLIPWS MIPDVVDLDE LNTGKRREGF FYAFMVLLQK VGLALGLFLV GLTLEASGFI
     ARIPGEPIPI QPDSALWAIR FAVAPLPAFF LLGGLILAIF YPITRAVHTD IRQQLQARQQ
     NNHI