ID   Y1375_METJA             Reviewed;         415 AA.
AC   Q58770;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 2.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Uncharacterized membrane protein MJ1375;
GN   OrderedLocusNames=MJ1375;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB99382.1; -; Genomic_DNA.
DR   PIR; F64471; F64471.
DR   RefSeq; WP_010870892.1; NC_000909.1.
DR   AlphaFoldDB; Q58770; -.
DR   SMR; Q58770; -.
DR   STRING; 243232.MJ_1375; -.
DR   EnsemblBacteria; AAB99382; AAB99382; MJ_1375.
DR   GeneID; 1452278; -.
DR   KEGG; mja:MJ_1375; -.
DR   eggNOG; arCOG02209; Archaea.
DR   HOGENOM; CLU_648322_0_0_2; -.
DR   InParanoid; Q58770; -.
DR   OMA; FIIIDSG; -.
DR   OrthoDB; 41033at2157; -.
DR   PhylomeDB; Q58770; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR029303; Polysacc_synt_C.
DR   InterPro; IPR002797; Polysacc_synth.
DR   Pfam; PF01943; Polysacc_synt; 1.
DR   Pfam; PF14667; Polysacc_synt_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..415
FT                   /note="Uncharacterized membrane protein MJ1375"
FT                   /id="PRO_0000166461"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        328..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        388..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   415 AA;  45989 MW;  EC0EC85C65BA7865 CRC64;
     MSLCKDSIYI LMSNLYSKGM AYLFYFITAF LLGTEAFGIL KGLMPIADTL TIFFSSGIPP
     AIAKFLAEEK EVDINKYIPI LYLMILLSVV GFILTPYIKY ILGGHYLNLP NILYFAVGLC
     VVASTVIAFS RGILQGLLKM KYLSLTWIVE YTAKVILVFI LTLYLGIFGS LLSISLAYLV
     GGIFGLYLIY KALKGKFDFK KLIDIKNTTK NIFSNFNLDI LRYSIPIALT SSSYRLFGDI
     DNIVIMSIMG GFWSGIYGYS SLISRGIFMF ASAVSIPLLP RISKTKDLSL LKEGIIQNTI
     FSSIFVIGCL FFPEIPLIAF FKTANPEGIL CLRILAISSL FMSYYTLISS ALQGLGYAKI
     SFYIILFGLV LNIILNLILV NAYGIVGGSL ATLITSISVF LIGVFAILRI KKHII