ID   Y1379_METKA             Reviewed;         350 AA.
AC   Q8TVL0;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=UPF0219 protein MK1379 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=MK1379;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
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DR   EMBL; AE009439; AAM02592.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TVL0; -.
DR   SMR; Q8TVL0; -.
DR   STRING; 190192.MK1379; -.
DR   EnsemblBacteria; AAM02592; AAM02592; MK1379.
DR   KEGG; mka:MK1379; -.
DR   PATRIC; fig|190192.8.peg.1534; -.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   OMA; YAKHKGK; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR013528; HMG_CoA_synth_N.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   Pfam; PF01154; HMG_CoA_synt_N; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..350
FT                   /note="UPF0219 protein MK1379"
FT                   /id="PRO_0000057615"
SQ   SEQUENCE   350 AA;  37598 MW;  FF7E0EA466074645 CRC64;
     MIPSERVGIV GYGAYVPRYR IKAEEIAAVW GDDVDSIKSG LMIEEKSVPS ETEDSATIAV
     EAAKNAVARA EIDPKDIGAI YVGSESPPYA VKPTATIVAA AIGATPDLTA ADYEFACKAG
     TAAIQTCAGL VASGMIKYGL AIGADTAQGA PGDPLEYTAA AGGAAFVIGR KKLVAEMEGT
     YSYTTDTPDF WRREGQPYPR HGGRFTGAPA YFKHIIRAAR GLMEELDLSP EDFDYAVFHQ
     PNGKFPRKVA RSLGFEPEQV EPTIVVDRVG NTYSGSSLLG FTAALDRAEP GDRILVVSYG
     SGAGSDAFSF VVTERIEEVR EKAPLLEEYL EDRVYVTYGE YAKMKKKLKF