Y1380_YERPE
ID Y1380_YERPE Reviewed; 382 AA.
AC Q8ZGC3; Q0WH35;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Uncharacterized MFS-type transporter YPO1380/y2792.1/YP_1213 {ECO:0000255|HAMAP-Rule:MF_01149};
GN OrderedLocusNames=YPO1380, y2792.1, YP_1213;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01149}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01149}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. YcaD (TC
CC 2.A.1.26) family. {ECO:0000255|HAMAP-Rule:MF_01149}.
CC -!- CAUTION: PubMed:12142430 (AE009952) sequence differs from that shown
CC due to the presence of an IS100 insertion sequence. This gene in strain
CC KIM5 may, therefore, be a pseudogene. {ECO:0000305}.
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DR EMBL; AL590842; CAL20032.1; -; Genomic_DNA.
DR EMBL; AE009952; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AE017042; AAS61456.1; -; Genomic_DNA.
DR PIR; AF0168; AF0168.
DR RefSeq; WP_002211335.1; NZ_VWRZ01000014.1.
DR RefSeq; YP_002346403.1; NC_003143.1.
DR AlphaFoldDB; Q8ZGC3; -.
DR SMR; Q8ZGC3; -.
DR STRING; 214092.YPO1380; -.
DR PaxDb; Q8ZGC3; -.
DR EnsemblBacteria; AAS61456; AAS61456; YP_1213.
DR GeneID; 66842160; -.
DR KEGG; ype:YPO1380; -.
DR KEGG; ypl:CH46_3748; -.
DR KEGG; ypm:YP_1213; -.
DR KEGG; ypv:BZ15_2173; -.
DR KEGG; ypw:CH59_461; -.
DR PATRIC; fig|214092.21.peg.1703; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_035018_1_2_6; -.
DR OMA; IGIGDHM; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01149; MFS_YcaD; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023745; MFS_YcaD.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..382
FT /note="Uncharacterized MFS-type transporter
FT YPO1380/y2792.1/YP_1213"
FT /id="PRO_0000084895"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 289..311
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01149"
SQ SEQUENCE 382 AA; 41687 MW; 455D9E04FEC94358 CRC64;
MSAYSRPVLL LLCGLLLFTI SIAVLNTLVP LWLSHQQLPT WQVGMVSSSY FTGNLVGTLI
AGRFIQQLGF NRSYHCSCIL FALATCGLML TVDFWSWLGW RFLAGIACAL IWVIVESALL
RSGTLTNRGQ LLAAYMMVYY LGTVIGQLLL GIVSTQLLSV IPWVGALVIT AMLPLLFAQF
SHQSRHESPP IAVWPMLKRR SARLGINGCI ISGVLLGSLY GLLPLYLSHK GMSDASVGGW
MALLVSSGII GQWPMGRMAD RYGRLLVLRI QVFVVILGSV AILGNYAMAP ALFILGCAGF
TLYPVAMAWA CEKASADELV AMNQALLMSY TLGSLAGPTM TSLLMQRYSD NLLFIMIAGV
AFVYLMMLLR KPDHQQTPYA AV
