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Y1382_METTH
ID   Y1382_METTH             Reviewed;         302 AA.
AC   O27435;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Uncharacterized transporter MTH_1382;
GN   OrderedLocusNames=MTH_1382;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69) family.
CC       {ECO:0000305}.
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DR   EMBL; AE000666; AAB85859.1; -; Genomic_DNA.
DR   PIR; H69050; H69050.
DR   AlphaFoldDB; O27435; -.
DR   STRING; 187420.MTH_1382; -.
DR   TCDB; 2.A.69.4.3; the auxin efflux carrier (aec) family.
DR   EnsemblBacteria; AAB85859; AAB85859; MTH_1382.
DR   KEGG; mth:MTH_1382; -.
DR   HOGENOM; CLU_056175_5_2_2; -.
DR   OMA; TTFFWTL; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR014024; Auxin_eff_plant.
DR   InterPro; IPR004776; Mem_trans.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   Pfam; PF03547; Mem_trans; 2.
DR   TIGRFAMs; TIGR00946; 2a69; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..302
FT                   /note="Uncharacterized transporter MTH_1382"
FT                   /id="PRO_0000123804"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   302 AA;  32047 MW;  9D3B1BA617AD42C0 CRC64;
     MIFMGSTETV LSVLVLVLLG YILKVLGVLG EEDASTLNRV VINVAIPSLI FTSLYRADLS
     GISDLVLIPV ICMITGTLSG TIAYLWARRR GLDSGKTWGL TVAAAMMNSG FLGYPVTAGI
     FGSEGLVRAI FYDTGTTLMF TSLGLLLSHI SGGEGSRIMK RAVFFPPLWA FLLGVIFNLW
     GLPTGIAGTI LGYLSGAAVP LIMISLGLTL NFRFLRHSVA DATLVSGLRL LISPLMAAGI
     SYVLAFRGLN FSVTVLEASM PSAMLAAVLA IENDLDVDLV SSCIFMSTIL SLVSLPLWSV
     VL
 
 
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