Y13P2_PLAF7
ID Y13P2_PLAF7 Reviewed; 685 AA.
AC Q8ID39;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Uncharacterized protein MAL13P1.336;
GN ORFNames=MAL13P1.336;
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000312|EMBL:CAD52789.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
RN [3] {ECO:0000305}
RP SYNTHESIS OF 388-414, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT "Rapid identification of malaria vaccine candidates based on alpha-helical
RT coiled coil protein motif.";
RL PLoS ONE 2:E645-E645(2007).
CC -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL844509; CAD52789.1; -; Genomic_DNA.
DR RefSeq; XP_001350380.1; XM_001350344.1.
DR AlphaFoldDB; Q8ID39; -.
DR BioGRID; 1209167; 24.
DR IntAct; Q8ID39; 24.
DR STRING; 5833.MAL13P1.336; -.
DR PRIDE; Q8ID39; -.
DR EnsemblProtists; CAD52789; CAD52789; PF3D7_1366900.
DR GeneID; 813903; -.
DR KEGG; pfa:PF3D7_1366900; -.
DR VEuPathDB; PlasmoDB:PF3D7_1366900; -.
DR HOGENOM; CLU_431813_0_0_1; -.
DR InParanoid; Q8ID39; -.
DR OMA; SAWKKKD; -.
DR Proteomes; UP000001450; Chromosome 13.
PE 1: Evidence at protein level;
KW Coiled coil; Merozoite; Reference proteome.
FT CHAIN 1..685
FT /note="Uncharacterized protein MAL13P1.336"
FT /id="PRO_0000361760"
FT REGION 78..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 86..139
FT /evidence="ECO:0000255"
FT COMPBIAS 84..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..607
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..657
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78574 MW; 5B626AD8C3F0ECCC CRC64;
MEDKEVVNSE NKVEVIKEEE NIKKEDDVTK KVSENTEDND ISLANNVSLG KHLLIGSSLK
KGISVSVRGR TMNLGMNAKQ AGSAWKKKET ENVEEEGEEK EKKIDDESFP DLLESTEKMK
SELSKEKDKK KKQLKDGKKV EDNVNVFNSG FDRGGKTTDG NSTEFNDKKK YNMYDGNKKN
DNAFNKKWYN NQQNDMNNNN QNNQNNMNNN NNNNNGHIFD TNESEEVTGY ILPGFKGKHM
VGFTCFLKRG TQNPVPPPPA PPLTNNQGEN NIPTDNRNNE NKKLMNTNIK MNQQVDNNNN
NNNNNNNLGS AMNTPMNNMN KGGPRNNVNN SEHMREHSNH TVNRFAPMGQ YANSKNNNMN
NVHNVNNVNN VNNVNNVNNV NNMNNMNNMN NMNNNMNNMN NNMNNNMNNM NNMNSMNSMN
NMNNMNSMNN MNNMNNMNNN NNNKFNENNI LYKGTNYNRN VKNLGQNNNE GNTNMKHGHN
NNRGQGNNNN NNNNNNFNRR NDKNDNRNFR RKDIDLEINW RNTANPTQEE NNNNMNHNNN
YNNNNNNNNN NNNNNNNNNN TNHGKNFRNF NNLNNMKNNN SSNNKMMGMN HMQQKGMNSS
TGGHKYSFNK NDDQKNNNKM YKNNMGNANN NNNNNAVNTN FNNNNNNGNF HMNNNKSINS
MDVKKTRMKD IRNLNDPPKV NNNEA
