ID   Y1401_METJA             Reviewed;         808 AA.
AC   Q58796;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Probable ATP-dependent helicase MJ1401;
DE            EC=3.6.4.-;
GN   OrderedLocusNames=MJ1401;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. {ECO:0000305}.
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DR   EMBL; L77117; AAB99409.1; -; Genomic_DNA.
DR   PIR; H64474; H64474.
DR   RefSeq; WP_010870918.1; NC_000909.1.
DR   AlphaFoldDB; Q58796; -.
DR   SMR; Q58796; -.
DR   STRING; 243232.MJ_1401; -.
DR   EnsemblBacteria; AAB99409; AAB99409; MJ_1401.
DR   GeneID; 1452304; -.
DR   KEGG; mja:MJ_1401; -.
DR   eggNOG; arCOG00554; Archaea.
DR   HOGENOM; CLU_010611_0_0_2; -.
DR   InParanoid; Q58796; -.
DR   OMA; SRRRCHE; -.
DR   OrthoDB; 3149at2157; -.
DR   PhylomeDB; Q58796; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR043852; DUF5814.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF19131; DUF5814; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..808
FT                   /note="Probable ATP-dependent helicase MJ1401"
FT                   /id="PRO_0000102014"
FT   DOMAIN          221..391
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          396..585
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           189..217
FT                   /note="Q motif"
FT   MOTIF           336..339
FT                   /note="DEIH box"
FT   BINDING         234..241
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   808 AA;  92933 MW;  C4F0DD8299BC0F0C CRC64;
     MLIVRKPKKK KDEIEIVKVG GKIEDGIEVK NNQKIFANYK KVGDKYKLYR CRVGDKLIQP
     SKVLELLKSD KIFILKENEE EIEEVLKSYN LKFDYIELCP FCLLKNIYKR LTRNNRCRYG
     NLEICINCGI NEIKEEVKIS EEFIEKFLKR FKDVDKVLSL LRIRNPLDKP ELTRYDIITG
     SEEDKIENYK IDELDIPEEL KEIIKSRGIE ELLPVQTLSV KAGLLNGDDL LIISATSSGK
     TLIGELAGIK NLIKTGKKFL FLVPLVALAN QKYLEFKERY EKLGFKVSLR VGLGRIGKKV
     DVETSLDADI IVGTYEGIDY LIRTKRLKDI GTVVIDEIHS LNLEERGARL DGLIGRLRFL
     FKEAQKIYLS ATIGNPKELA KQLNAKLVLY NGRPVPLERH IIFCKNDFAK LNIIKEIVKR
     EWQNISKFGY RGQCLIFTYS RKRAEYLAKA LKSKGIKAEF YHGGMEYIKR RKVEDDFANQ
     KIQCVVTTAA LSAGVDFPAS TVILESLAMG ADWLNPAEFQ QMCGRAGRKG MHEIGKVYLL
     VEIGKKYHAK MENTEDEVAF KLLNAVPEDV KVEYNEDEEE EQILATISAG ITNRYDIDRV
     PYIGRAFSLN KILSNLESYG MIKANNDVKL TNYGSAVAIS FLYPKVAEKI KEGIIENKEI
     IKLITEIMPF ENVYLSNNLK IKLSKILNIN VPSRFFDALE VIREGMEKIK DKKLKEDLTL
     IIMEFEGVEV EEKILEMIIN LRISGKTPGQ ISKTLYEEFK IQTYSGDIYY YLEQLLNLLD
     ATERIARIFN KRYAEKVKEL KEKIENPK