ID   Y1416_COXBU             Reviewed;         216 AA.
AC   Q83BT6;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator CBU_1416;
GN   OrderedLocusNames=CBU_1416;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND DEVELOPMENTAL STAGE.
RC   STRAIN=Nine Mile Crazy / RSA 514;
RX   PubMed=17088354; DOI=10.1128/iai.00883-06;
RA   Coleman S.A., Fischer E.R., Cockrell D.C., Voth D.E., Howe D., Mead D.J.,
RA   Samuel J.E., Heinzen R.A.;
RT   "Proteome and antigen profiling of Coxiella burnetii developmental forms.";
RL   Infect. Immun. 75:290-298(2007).
CC   -!- DEVELOPMENTAL STAGE: More than twofold more abundant in the large cell
CC       variant (LCV) stage than in the small cell variant (SCV) stage (at
CC       protein level). LCVs are more metabolically active than SCVs.
CC       {ECO:0000269|PubMed:17088354}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO90914.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016828; AAO90914.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_820400.2; NC_002971.3.
DR   AlphaFoldDB; Q83BT6; -.
DR   STRING; 227377.CBU_1416; -.
DR   EnsemblBacteria; AAO90914; AAO90914; CBU_1416.
DR   GeneID; 1209322; -.
DR   KEGG; cbu:CBU_1416; -.
DR   PATRIC; fig|227377.7.peg.1416; -.
DR   eggNOG; COG1974; Bacteria.
DR   HOGENOM; CLU_1293816_0_0_6; -.
DR   OMA; NGNCTIV; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd06529; S24_LexA-like; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR039418; LexA-like.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   Pfam; PF13443; HTH_26; 1.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..216
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   CBU_1416"
FT                   /id="PRO_0000324817"
FT   DOMAIN          8..63
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   216 AA;  24286 MW;  52B33E9D4BB9C663 CRC64;
     MASLSSNLKT LMTSVHINAS ELARRTGIAQ PIIHRLSTGQ NTNPKLATIK PIARYFMVNI
     SQLIGEEPLP SDQSPQITGN YRAWNRVPLI SWKDATSWPE ALPHYQTSDE VMYISTDANV
     SKLAYGLIIQ GCAMEPLFPN GTTIIVEPER KPKDRDFVVV RLQGEPEARL RQIITEGNDR
     YLKSLNPELE KLEVARLAQE DQFLGVMAQA KVDFLR