ID   Y1421_ARCFU             Reviewed;         880 AA.
AC   O28851;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=UPF0182 protein AF_1421 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=AF_1421;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; AE000782; AAB89825.1; -; Genomic_DNA.
DR   PIR; D69427; D69427.
DR   RefSeq; WP_010878918.1; NC_000917.1.
DR   AlphaFoldDB; O28851; -.
DR   SMR; O28851; -.
DR   STRING; 224325.AF_1421; -.
DR   EnsemblBacteria; AAB89825; AAB89825; AF_1421.
DR   GeneID; 24795033; -.
DR   KEGG; afu:AF_1421; -.
DR   eggNOG; arCOG06128; Archaea.
DR   HOGENOM; CLU_007733_0_0_2; -.
DR   OMA; HLRYPQD; -.
DR   OrthoDB; 4310at2157; -.
DR   PhylomeDB; O28851; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..880
FT                   /note="UPF0182 protein AF_1421"
FT                   /id="PRO_0000157732"
FT   TRANSMEM        19..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        61..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        103..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        152..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        195..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        237..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        268..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
SQ   SEQUENCE   880 AA;  102211 MW;  8AD99AB7B4E50671 CRC64;
     MQEPPVYPPP YKPPEMKVFY FLAFVFGLVI VISLSIYYYT EMLWFESVGY ENVFLTYLKH
     SLGFFFLEFI IFFVPLFLTN VAVRKVTLEF HGEPLKIPHL ADFGIAFFAA LTVKNYWSSM
     LFYFNSSNFG VSDPIFGIDA AFYTFQLPFL KIVIGSLLAA LLISLAIAAF AYMYAFRWVK
     SLEEFKEIFP GSGFMHFSAL LFASFLLSAA LIYLSRFEIV HSEHGLISGA SYVDVNILSP
     SLMFLSAIVL LSGIFAAYIV ARRRVERVFQ IVGVLFVIAI LLTFVAPFFV QKFVVEPSEL
     SYEGRYIAYS INYTLFAYNL HDVKLQKFDY WDVVNYNDIL EAKDTIDNIR IWDHRPIRDV
     FRQLQQIRTY YVIQDVDVDR YRINDSYVQL LLAARELSTE NLPSRAQTWL NKHLIYTHGY
     GIVASPVNKV SKEGLPEFYI YDIPPEGLIK IERPEIYYGE LTDDYVVVNT LQEEFDYPKG
     DVNFFTKYAG DGGIKLDYFR KVLFSFRFGD INLILSNYIT DESRLMMHRD IVERVSTIMP
     FFVYDDDPYV AVIDGEIWWI IDAYSVLQNF PYSAEVRGFN YMQNPVKVFV NAYNGSVRFY
     VVQEDAYVRA LEKALPGVFL KDMPEEFRKH IRYPRDYFEV QAHIYSTYHM KDVTAFYNRE
     DVWAVAKEKY EDDVIEVEPY YVTLAIEDKP EFILMLPMTP VNRDNMIAWM AARCDEKYGE
     LIIYEFPKGE LIYGPMQIEA RIDQDSELSK LFTLWNQAGS RVIRGNLLVV PINHSVLYVE
     PVYLRGESAK IPELRLVIVV QDEELATGTN LYEALENLFK GEKPAEKPAT PEKPSETVEE
     KLEILREYYS KLVDAAKNGD WETFGEMLKK IGEVLGYEGE