ID   Y1427_STAEQ             Reviewed;         328 AA.
AC   Q5HN45;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=UPF0421 protein SERP1427;
GN   OrderedLocusNames=SERP1427;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; CP000029; AAW54799.1; -; Genomic_DNA.
DR   RefSeq; WP_002457091.1; NC_002976.3.
DR   AlphaFoldDB; Q5HN45; -.
DR   SMR; Q5HN45; -.
DR   STRING; 176279.SERP1427; -.
DR   EnsemblBacteria; AAW54799; AAW54799; SERP1427.
DR   GeneID; 50018326; -.
DR   KEGG; ser:SERP1427; -.
DR   eggNOG; COG4129; Bacteria.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   OrthoDB; 1974930at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SERP1427"
FT                   /id="PRO_0000283023"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37351 MW;  71D748C20DC30A33 CRC64;
     MNDKWYRHII GARTIKTGLA TFFTSLFCML LNLTPIFAIL TAIVTIEPTA KASLKKGYKR
     LPATVIGALF AVVFTYVFGD QSPLSYALSA TFTILICTKL NLQVGTTVAV LTSVAMIPGI
     HEAYVFNFFS RLLTALIGLV TAGLVNFIIL PPKYYHQLEE QLALSEKKMY RLFYERCNEL
     LLGKFSSEKT SKELSKLNII AQKVETLMSY QRDELHYHKN EDNWKLLNRL TNRAYNNRLF
     ISHLSNIIYL PKHTSIAFDA NEKIALINIS NSINGIIQKG SFARQKKSIA TLKSSVKQMD
     EFDQNQMKST LIYEILLIYK ILDSRYAK