Y1429_HELPY
ID Y1429_HELPY Reviewed; 329 AA.
AC O25971;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Uncharacterized protein HP_1429;
GN OrderedLocusNames=HP_1429;
OS Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85962;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700392 / 26695;
RX PubMed=9252185; DOI=10.1038/41483;
RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT "The complete genome sequence of the gastric pathogen Helicobacter
RT pylori.";
RL Nature 388:539-547(1997).
CC -!- SIMILARITY: Belongs to the SIS family. GutQ/KpsF subfamily.
CC {ECO:0000305}.
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DR EMBL; AE000511; AAD08468.1; -; Genomic_DNA.
DR PIR; E64698; E64698.
DR RefSeq; NP_208220.1; NC_000915.1.
DR RefSeq; WP_001121932.1; NC_018939.1.
DR AlphaFoldDB; O25971; -.
DR SMR; O25971; -.
DR STRING; 85962.C694_07390; -.
DR PaxDb; O25971; -.
DR EnsemblBacteria; AAD08468; AAD08468; HP_1429.
DR KEGG; hpy:HP_1429; -.
DR PATRIC; fig|85962.47.peg.1533; -.
DR eggNOG; COG0517; Bacteria.
DR eggNOG; COG0794; Bacteria.
DR OMA; LMACLMR; -.
DR PhylomeDB; O25971; -.
DR Proteomes; UP000000429; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05014; SIS_Kpsf; 1.
DR Gene3D; 3.10.580.10; -; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR004800; KdsD/KpsF-type.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035474; SIS_Kpsf.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01380; SIS; 1.
DR PIRSF; PIRSF004692; KdsD_KpsF; 1.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF53697; SSF53697; 1.
DR TIGRFAMs; TIGR00393; kpsF; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW ATP-binding; CBS domain; Nucleotide-binding; Reference proteome; Repeat.
FT CHAIN 1..329
FT /note="Uncharacterized protein HP_1429"
FT /id="PRO_0000136587"
FT DOMAIN 38..184
FT /note="SIS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT DOMAIN 211..267
FT /note="CBS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT DOMAIN 270..329
FT /note="CBS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT BINDING 56..61
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 329 AA; 35784 MW; E93CDDB1D4E8056F CRC64;
MPILFDCNAI ASQVLKDEAS ALLESVGQFQ KPNDLEAIVK LILKSQENGG KLVIVGVGKS
ALVAQKIVAS MLSTGNRSAF LHPTEAMHGD LGMVEKNDVV LMISYGGESL ELLNLVSHLK
RLSHKIITFT KSPNSSLSKL GDYYLSLKIQ KEACPINTAP TTSTTLTLAL GDVLMACLMR
AKNFSQEDFA SFHPGGLLGK KLFVKVKDLL QTTNLPLIAP STSFKDALIE MSEKRLGSAI
LVNEANELVG VLSDGDVRRA LLKGVSLKSE VRHFATLKPK SFKNLDALLL EALEFLERHK
IQLLVCVDDH NKVLGVLHLH QLLELGLKA
