ID   Y1430_MYCTA             Reviewed;         301 AA.
AC   A5U2C3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Nucleotide-binding protein MRA_1430 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=MRA_1430;
OS   Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=419947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25177 / H37Ra;
RX   PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA   Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA   Wang H., Wang S., Zhao G., Zhang Y.;
RT   "Genetic basis of virulence attenuation revealed by comparative genomic
RT   analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL   PLoS ONE 3:E2375-E2375(2008).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000611; ABQ73173.1; -; Genomic_DNA.
DR   RefSeq; WP_003898873.1; NZ_CP016972.1.
DR   AlphaFoldDB; A5U2C3; -.
DR   SMR; A5U2C3; -.
DR   STRING; 419947.MRA_1430; -.
DR   EnsemblBacteria; ABQ73173; ABQ73173; MRA_1430.
DR   GeneID; 45425399; -.
DR   KEGG; mra:MRA_1430; -.
DR   eggNOG; COG1660; Bacteria.
DR   HOGENOM; CLU_059558_0_0_11; -.
DR   OMA; TVMSFGF; -.
DR   OrthoDB; 1603998at2; -.
DR   Proteomes; UP000001988; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..301
FT                   /note="Nucleotide-binding protein MRA_1430"
FT                   /id="PRO_1000056837"
FT   BINDING         24..31
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         75..78
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   301 AA;  32912 MW;  FB546C303B51C01A CRC64;
     MMNHARGVEN RSEGGGIDVV LVTGLSGAGR GTAAKVLEDL GWYVADNLPP QLITRMVDFG
     LAAGSRITQL AVVMDVRSRG FTGDLDSVRN ELATRAITPR VVFMEASDDT LVRRYEQNRR
     SHPLQGEQTL AEGIAAERRM LAPVRATADL IIDTSTLSVG GLRDSIERAF GGDGGATTSV
     TVESFGFKYG LPMDADMVMD VRFLPNPHWV DELRPLTGQH PAVRDYVLHR PGAAEFLESY
     HRLLSLVVDG YRREGKRYMT IAIGCTGGKH RSVAIAEALM GLLRSDQQLS VRALHRDLGR
     E