Y143_HAEIN
ID Y143_HAEIN Reviewed; 288 AA.
AC P44540;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator HI_0143;
GN OrderedLocusNames=HI_0143;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
RN [2]
RP SEQUENCE REVISION.
RA White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D.;
RL Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; L42023; AAC21815.1; -; Genomic_DNA.
DR RefSeq; NP_438312.1; NC_000907.1.
DR RefSeq; WP_010868944.1; NC_000907.1.
DR AlphaFoldDB; P44540; -.
DR SMR; P44540; -.
DR STRING; 71421.HI_0143; -.
DR EnsemblBacteria; AAC21815; AAC21815; HI_0143.
DR KEGG; hin:HI_0143; -.
DR PATRIC; fig|71421.8.peg.145; -.
DR eggNOG; COG1737; Bacteria.
DR HOGENOM; CLU_055769_0_3_6; -.
DR OMA; QEDTEIY; -.
DR PhylomeDB; P44540; -.
DR BioCyc; HINF71421:G1GJ1-155-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF53697; SSF53697; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..288
FT /note="Uncharacterized HTH-type transcriptional regulator
FT HI_0143"
FT /id="PRO_0000068627"
FT DOMAIN 5..81
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
FT DOMAIN 129..269
FT /note="SIS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT DNA_BIND 41..60
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
SQ SEQUENCE 288 AA; 31465 MW; FBC951EAFE6FB4A4 CRC64;
MAKSGNVLNK IGSLYQSLTK SEKKIADTIL RSPDLVSQCS LSEIAKHLQV GEATLVRFCR
TIGFKGFSEF KLELSIELAT KDNQDESILE TEIMPSDDSL TIAQKLQTAV ANVMEETINL
LDLKQLEEVV KVLKKARRIF LFGVGSSGVT AEDAKNKLMR IGFQVDASGN NHFMYMQAAL
LTSSDVAIGL SHSGYSAETA HTIKIAKQNG ATTVALTHSL RSPVTEYADY VLVNGNKQGK
LQGDSIGTKI AQLFVLDLIY ALLVQGEEDI AAQTKQKTLN VILEQRIK
