ID   Y143_RICCN              Reviewed;         661 AA.
AC   Q92JC4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Uncharacterized protein RC0143;
DE   Flags: Precursor;
GN   OrderedLocusNames=RC0143;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; AE006914; AAL02681.1; -; Genomic_DNA.
DR   PIR; G97717; G97717.
DR   RefSeq; WP_010976820.1; NC_003103.1.
DR   AlphaFoldDB; Q92JC4; -.
DR   PRIDE; Q92JC4; -.
DR   EnsemblBacteria; AAL02681; AAL02681; RC0143.
DR   KEGG; rco:RC0143; -.
DR   PATRIC; fig|272944.4.peg.167; -.
DR   HOGENOM; CLU_027273_0_0_5; -.
DR   OMA; GGADKCQ; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..661
FT                   /note="Uncharacterized protein RC0143"
FT                   /id="PRO_0000269208"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        469..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          629..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  72157 MW;  A6F0B1B9D37E06CB CRC64;
     MKTLKTLKIF IIVFIASVSL ASFAGFGESC SSLPTTSDGY LETDTAYGYI IRNIDMKDPR
     GNCNSVASSI TFCFKNVEGS SSPCTMYTLN EGDSKKISDL STDNNPDLGA NPVLKNIVLT
     VKKWDNDLCL VMPTSRGPMP VACKSLSATP TPPPSEDKNC NIGKSCYTGA NYSQSLINFS
     GLAVQCLSET LNKIFFAGKS CSAQDQNSRI TNLAAFSTFQ GYLKRIIGAA LILYTMFFAF
     NMALNTEYAS TEKIALFVIK FLFVAYFSIG LGPLDFSGGQ PTKENGMLKY GLPLLTGAAP
     DFAQMIFNAA GSRGLCQFDN SKYKDGYKFY GLWDAIDCRI GYYLGLDLLY NIDKNRVLGN
     VVGNGPRGNN TPIPNFDPEG KNDRPKDLSK AGALRFFTVM FGFFMAGNVI ILAAGLVFSV
     IFLSILLYFI THYLVCMITI YVMTYISPIF IPMALFTRTK AYFDGWLKVC ISCALQPAVV
     AGFIALLITM YDSAIFKNCE FLRYDYERGD IRFSTFELRL PVGGADKCQE SFGYKMLEYY
     AGKGWEEHLL ILFPIKSIVR DVVSILAELL CVLVFSVIFY YFSKSIGRFA SDLTNGPNMD
     AVTASPTKIV GLVKKGAAFL KDAAMASQGK PLVGDKPGVG GKRKEGEQQG GDLASGSGGG
     K