CAPSD_FMVD
ID CAPSD_FMVD Reviewed; 489 AA.
AC P09519;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 02-JUN-2021, entry version 83.
DE RecName: Full=Probable capsid protein;
DE Short=CP;
DE AltName: Full=Coat protein;
GN ORFNames=ORF IV;
OS Figwort mosaic virus (strain DxS) (FMV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Caulimoviridae; Caulimovirus.
OX NCBI_TaxID=10650;
OH NCBI_TaxID=46031; Scrophularia californica (California bee plant).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3671088; DOI=10.1093/nar/15.20.8451;
RA Richins R.D., Scholthof H.B., Shepherd R.J.;
RT "Sequence of figwort mosaic virus DNA (caulimovirus group).";
RL Nucleic Acids Res. 15:8451-8466(1987).
CC -!- FUNCTION: Self assembles to form an icosahedral capsid, about 50 nm in
CC diameter, nm, composed of 420 subunits of the viral capsid protein. The
CC capsid encapsulates the genomic dsDNA. Following virus entry into host
CC cell, provides nuclear import of the viral genome. Virus particles do
CC not enter the nucleus, but dock at the nuclear membrane through the
CC interaction with host importins (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts (via nuclear localization signal) with host importin
CC alpha. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the caulimoviridae capsid protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X06166; CAA29526.1; -; Genomic_DNA.
DR PIR; S01282; VCCVFM.
DR RefSeq; NP_619547.1; NC_003554.1.
DR SMR; P09519; -.
DR GeneID; 940155; -.
DR KEGG; vg:940155; -.
DR Proteomes; UP000008622; Genome.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0039620; C:T=7 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR InterPro; IPR001988; Caulimo_coat.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PRINTS; PR00221; CAULIMOCOAT.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF57756; SSF57756; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW Capsid protein; Host nucleus; Metal-binding; Reference proteome;
KW T=7 icosahedral capsid protein; Viral penetration into host nucleus;
KW Virion; Virus entry into host cell; Zinc; Zinc-finger.
FT CHAIN 1..489
FT /note="Probable capsid protein"
FT /id="PRO_0000222035"
FT ZN_FING 409..426
FT /note="CCHC-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT REGION 87..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 107..110
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250"
SQ SEQUENCE 489 AA; 57419 MW; D9D19FE4C6F8D782 CRC64;
MATKKMRISE KLWDSLEKDE CNIDEVVQLM SLDEEELITK FAQEVSLRIR YLDEKPNEIS
FIAEATEDYS EPETESSDEE TYFQQIRMER GESSETKREQ QDLGATRKRK IEERNPFYTP
PVHKGIPSST GRGTEISTLN LDCISSFEER KVMIDKWFNE ISLIIQTNKE SFDTSLKVLT
LMEHRTEGIA KSFIKQATWD ILITPEKIIE EVLTGFYTMF IGLDYALSAE KEEEKRIKKA
EELLIKSQLC NICELDNFTC FYEKQINQLK FEDFPKWIEL YLGKIPIIGK QSKERWDNEK
SFTTKYSLAF AKRIIQEEIA KYCDFQRTSK KLKNFSKKCC SKNSLDPLVS FGCRDTKKKD
FKKSSKYKAY KKKKTLKKLW KKKKRKFTPG KYFSKKKPEK FCPQGRKKCR CWICTEEGHY
ANECPNRKSH QEKVKILIHG MNEGYYPLED AYTGNLEVFS MEIIEETTSE EESTTDSDSS
SSDDEQLSF
