Y1448_ARATH
ID Y1448_ARATH Reviewed; 498 AA.
AC A5PHT0; A5PHT1;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Uncharacterized protein At1g24485;
DE AltName: Full=Arabidopsis thaliana envelope membrane integrase;
DE Short=Protein ARTEMIS;
DE AltName: Full=Receptor without kinase 1;
DE Flags: Precursor;
GN Name=RWK1; Synonyms=ART1; OrderedLocusNames=At1g24485; ORFNames=F21J9.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RA Gerdes L.;
RT "Protein import into chloroplasts.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1; Synonyms=rwk1.1;
CC IsoId=A5PHT0-1; Sequence=Displayed;
CC Name=2; Synonyms=rwk1.2;
CC IsoId=A5PHT0-2; Sequence=VSP_036316;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF97960.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC000103; AAF97960.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30536.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30537.1; -; Genomic_DNA.
DR EMBL; AM746461; CAN89261.1; -; mRNA.
DR EMBL; AM746462; CAN89262.1; -; mRNA.
DR RefSeq; NP_001117345.1; NM_001123873.1. [A5PHT0-2]
DR RefSeq; NP_001117346.1; NM_001123874.1. [A5PHT0-1]
DR AlphaFoldDB; A5PHT0; -.
DR SMR; A5PHT0; -.
DR PaxDb; A5PHT0; -.
DR ProteomicsDB; 242436; -. [A5PHT0-1]
DR EnsemblPlants; AT1G24485.1; AT1G24485.1; AT1G24485. [A5PHT0-2]
DR EnsemblPlants; AT1G24485.2; AT1G24485.2; AT1G24485. [A5PHT0-1]
DR GeneID; 6240649; -.
DR Gramene; AT1G24485.1; AT1G24485.1; AT1G24485. [A5PHT0-2]
DR Gramene; AT1G24485.2; AT1G24485.2; AT1G24485. [A5PHT0-1]
DR KEGG; ath:AT1G24485; -.
DR Araport; AT1G24485; -.
DR eggNOG; ENOG502QVXJ; Eukaryota.
DR InParanoid; A5PHT0; -.
DR PhylomeDB; A5PHT0; -.
DR PRO; PR:A5PHT0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A5PHT0; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR Pfam; PF12819; Malectin_like; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..498
FT /note="Uncharacterized protein At1g24485"
FT /id="PRO_0000363608"
FT TOPO_DOM 27..441
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 463..498
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 351..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 44
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 150
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 354
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 357
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 406..425
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_036316"
FT CONFLICT 46
FT /note="T -> A (in Ref. 1; CAN89261/CAN89262)"
FT /evidence="ECO:0000305"
FT CONFLICT 420
FT /note="E -> G (in Ref. 1; CAN89261)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 498 AA; 53041 MW; 257113DF118AA8A2 CRC64;
MEESSMAQAS LICLLLSFSI IMLSNAADIS IDCGSSSSHI DADNRTWVGD TDFVATGLTS
KFVPFSKFPA ELTTLRYFPT GETNCYTNIP VEKGGKVLVR TRFLYGDYDE ESTYPTFDVV
YDGKHRYSVV TTTFETVTES EAIFIPENGN ISVCFFRTLS SKTPFVSTIE VRRLDDSMYT
DLGPKEGFIL QQRIAYGAQE LVRFPYDPYD RIWMPASVFA SHLTSSATSI DTTGADNRPP
EIILRTSWSQ KDMAFYDIKL PFSGVTFYIV IYFSEPLSLG SDQKRSFNVY YEDKQVGSDL
IVPPFGAVTQ ASLRDVVKTE LAYLTFEATP DSTLDPLINA LELYVISNSG GSGNGTNSTS
TSGGGSPSPG GGSGSPPSTG GGSGSPPSTG GGGGSPSKGG GGGKSGGSNN GDGGTNKASE
DEKSADSSGK SGEEKSSSNL ALPLGISLPT LLSLGAGGWG VWKYFIKPRR HPESELPLKQ
NISLQVNMGN ATVVNAGQ
