ID   Y1460_VIBCH             Reviewed;         395 AA.
AC   P38443; Q9KS09; Q9L7Q7;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized protein VC_1460;
DE   AltName: Full=OrfU;
GN   OrderedLocusNames=VC_1460;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 55056 / El Tor Ogawa E7946;
RX   PubMed=8389476; DOI=10.1073/pnas.90.11.5267;
RA   Trucksis M., Galen J.E., Michalski J., Fasano A., Kaper J.B.;
RT   "Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae
RT   virulence cassette.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:5267-5271(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=El Tor 86015 / Serotype O1;
RA   Kan B., Liu Y.Q., Qi G.M., Gao S.Y.;
RT   "Vibrio cholerae nct-CTXphi whole genome, include rstR(RstR), rstA(RstA),
RT   rstB(RstB), cep(Cep), orfU(OrfU), ace(Ace) and zot(Zot) genes.";
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF94617.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; Z22569; CAA80291.1; -; Genomic_DNA.
DR   EMBL; AF220606; AAF29545.1; -; Genomic_DNA.
DR   EMBL; AE003852; AAF94617.1; ALT_INIT; Genomic_DNA.
DR   PIR; D82197; D82197.
DR   PIR; S36029; S36029.
DR   RefSeq; NP_231103.1; NC_002505.1.
DR   RefSeq; WP_001268534.1; NZ_LT906614.1.
DR   AlphaFoldDB; P38443; -.
DR   SMR; P38443; -.
DR   STRING; 243277.VC_1460; -.
DR   DNASU; 2613966; -.
DR   EnsemblBacteria; AAF94617; AAF94617; VC_1460.
DR   GeneID; 57740123; -.
DR   KEGG; vch:VC_1460; -.
DR   PATRIC; fig|243277.26.peg.1390; -.
DR   eggNOG; ENOG50308DC; Bacteria.
DR   HOGENOM; CLU_698180_0_0_6; -.
DR   OMA; CSYVEEF; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   Gene3D; 2.40.30.280; -; 1.
DR   InterPro; IPR032014; CTXphi_pIII-N1.
DR   InterPro; IPR038618; CTXphi_pIII_N1_sf.
DR   Pfam; PF16710; CTXphi_pIII-N1; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..395
FT                   /note="Uncharacterized protein VC_1460"
FT                   /id="PRO_0000203505"
FT   REGION          247..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        306
FT                   /note="E -> A (in Ref. 2; AAF29545)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   395 AA;  43975 MW;  CCCDD789953B86FD CRC64;
     MRYFLLFLTL LFLSPSVTAS AINCDPNTTT SHQLLFGFGS PIVQSVLFDG CMLDIEKDDY
     GFVWSCLSNE NGDYCKGLYK PRFSQGVSPN WPMCDLSGAS AERCIYPYCP EGEECVPLPP
     SPPSDSPVDG LSSSFKSAFN QVYKNQSEMA STLNHVSGQV SHSQDMVQLN TKFHADRVLE
     SVTAVNNRLG GQMEYLEEIR IDVWDTQREV RKAKDELYSR VAAVSYDVLY SELNVLRAID
     ELKDSLGGTV VPPNPDQPNP TPPDSSSPNY TGALNTISKK LNTLETISQQ LDTMNTALSG
     RCSNPERCQF PIREAETELE TAQQNLKQMI NEKITQSALH QFKGSAAVPS FCSYVEAFGY
     NLCFDFSLFS ENLHIIRMIV LAMAYILAAM LILFR