ID   Y1468_METJA             Reviewed;        1009 AA.
AC   Q58863;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Uncharacterized protein MJ1468;
GN   OrderedLocusNames=MJ1468;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L77117; AAB99478.1; -; Genomic_DNA.
DR   PIR; C64483; C64483.
DR   RefSeq; WP_010870988.1; NC_000909.1.
DR   AlphaFoldDB; Q58863; -.
DR   SMR; Q58863; -.
DR   STRING; 243232.MJ_1468; -.
DR   EnsemblBacteria; AAB99478; AAB99478; MJ_1468.
DR   GeneID; 1452372; -.
DR   KEGG; mja:MJ_1468; -.
DR   eggNOG; arCOG02508; Archaea.
DR   eggNOG; arCOG03991; Archaea.
DR   HOGENOM; CLU_294353_0_0_2; -.
DR   InParanoid; Q58863; -.
DR   OMA; WCGYLNN; -.
DR   OrthoDB; 2301at2157; -.
DR   PhylomeDB; Q58863; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 5.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR026495; PIP_CTERM.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   SMART; SM00089; PKD; 7.
DR   SUPFAM; SSF49299; SSF49299; 5.
DR   TIGRFAMs; TIGR04173; PIP_CTERM; 1.
DR   PROSITE; PS50093; PKD; 5.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..1009
FT                   /note="Uncharacterized protein MJ1468"
FT                   /id="PRO_0000107354"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        985..1005
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          213..247
FT                   /note="PKD 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00151"
FT   DOMAIN          436..503
FT                   /note="PKD 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00151"
FT   DOMAIN          724..806
FT                   /note="PKD 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00151"
FT   DOMAIN          822..886
FT                   /note="PKD 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00151"
FT   DOMAIN          925..962
FT                   /note="PKD 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00151"
SQ   SEQUENCE   1009 AA;  115120 MW;  13E9B4933EAB7972 CRC64;
     MKLLKILMPL IILGIISIVN GYVIVIHPNT MNITNSSGVY NTDPNIIAYN VNDTITFEAL
     APDSVAQDIL DNGVVKWDFG DLTETDYGNY RTTTHTYTFP FPYPVAWCGY LNNTGYSKAL
     TYNWLVVGDV ANTKYVFNGS PLNSKTSWEV YYNSTNNTVI IKYYSETPVD REFNGLSVDT
     TSVTVNVSRD EIVEGDTVKF NFSVSRNIIF CVWSFGDGTF SFEKFPEHTY TKSGLYYPRV
     LVVDDSGRVM VGYLDEGIEV KRARGGYIYW VTGPSHYDGE AYTYVYNSSG DDNNNNGNAY
     TDPYKITYKV NDTIKFEMSG AWGEYWKWDF GDGTETPYTY KSYFTPSYHQ YKFPFMWPFF
     WMSYGWGSWW KSDTLNFIVV DDVENTRYNF YPSSAHDKTY YDYEYNKENH TVNLYYYSDV
     ISTPKFNVKL RDGYYIDITA TADKTQVSVN ENVRFDCSPY GNPIFIMWCF GDGTCSFEKS
     PTHRYSSSGL YYPHVFVIDD NGNIEVGIPP PIGVGGYSSY PQIYASPTIA PTYYPINITI
     VEPASWTWYW HHIYFGDGGS VWIKPKKSPY TFTHTYTSEG VYPIYMKVYT AENMKTVYVI
     DNKNPIAKLY IYPNPASYKD TISFSPINSY DPDANRMIPE YNYYGTLIGY YPISPNSPMA
     RIYGFNLTVY DSNGNVAWNY SSNELTIISK SFPIGNYTAK LVVWDGMGGV NSTTVKFSVI
     NRPPVAQFIY YPDKPEPNED VEFVSQSYDP EGEIAYYIWN FGDGTVINTT DTIVHHKYER
     PGYYTVTLTV FDKYNASSSI SKQIVVGGIL ANFTYEIINE NTVRFEDTSV VAPGKIISWH
     WDFGDGSTST EQNPIHTYSK EGAYFVTLTV KSDTNLTDSV TKIVIISPPP KYPPVADFTY
     KVINGTTVEF NANLSYDEDG YIKYYIWDFG DGTPANTTTN PIIIHKYKKE GVYPVTLTVI
     DNDNLSDSRT KLINIGESFI HSVPIPPYIE ILIVISTIFC FFQIIRGLK