ID   Y146_RICCN              Reviewed;        1153 AA.
AC   Q92JC1;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Uncharacterized lipoprotein RC0146;
DE   Flags: Precursor;
GN   OrderedLocusNames=RC0146;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Multi-pass membrane protein {ECO:0000305}. Cell
CC       membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the TrbL/VirB6 family. {ECO:0000305}.
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DR   EMBL; AE006914; AAL02684.1; -; Genomic_DNA.
DR   PIR; B97718; B97718.
DR   RefSeq; WP_010976823.1; NC_003103.1.
DR   AlphaFoldDB; Q92JC1; -.
DR   SMR; Q92JC1; -.
DR   PRIDE; Q92JC1; -.
DR   EnsemblBacteria; AAL02684; AAL02684; RC0146.
DR   KEGG; rco:RC0146; -.
DR   PATRIC; fig|272944.4.peg.170; -.
DR   HOGENOM; CLU_275941_0_0_5; -.
DR   OMA; ECIDERY; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030255; P:protein secretion by the type IV secretion system; IEA:InterPro.
DR   InterPro; IPR007688; Conjugal_tfr_TrbL/VirB6.
DR   Pfam; PF04610; TrbL; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           19..1153
FT                   /note="Uncharacterized lipoprotein RC0146"
FT                   /id="PRO_0000269910"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        422..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   1153 AA;  131619 MW;  A869C596FE0C29B0 CRC64;
     MNKNIFITLL ISLLLLSGCT GDTCIDPDDF GFIKFNVSAR YDPEEITSRQ EGNQVAPWRD
     SAYKVNGYPL TIMVRPWSYI LGDKNTSGQL SAWCPWYGQK NNTTTLAAFC VKLQPCTFWD
     NTRLDMCTPN PANQNDAMIS NAPCIMTNGV GLYFLIAAKN TDPNISPDSQ SKPQGITQHL
     GEELTSGYEF YSTSSTGQFS KAGGINYQYK GEDKSKYAQS PLYFKIIDKF YNDNSGQYRL
     VIKSGVTDTR ADPLQFLTDL IKGVLFGKDG IIKKTYQQII DTSGYRMSVS AILTLYIMFT
     GFSFLIGNIN LTHVELIVRI LKVSIVSILL STDKAWTFFH DYLFVFFIDG VQQILQIINE
     ASATGPGSQS LLGLLISPQT LSKLFSLLFV DWLGFIYIIL YLIALYFIFF LIFKATIIYL
     TALITIGMII IMGPIFICFM LFNITRSLFE NWLRQLISYA LQPIILFTGI AFISMIIRTE
     IYSTLGFAVC KHDFPNLGPI NEIFGSFLED IDPSLGHSIF YWWFPVPMKG GINNFHKANI
     LVPKDHIVVD DSCKNDPDKC KHCAAYECID ERYIELPFLD LVKDAKRISN FINGKFVQLD
     GILLIFVSIY LLSKFNDTAI STAQFIAGTS GNLTEIQKVN QQSYESAAKQ MNRPLNYVAK
     TVSAPVTSRV SAGKEQVRMF FAEKFENMMM GRLEKQALGS SANKTVQNEV KRKYGIDSKD
     VKMNAITDYE NGIAGLLKNL PKGNELKAKE LSQMKFTQLR DKIAANKYGV KDYAALSKEQ
     KAELDKSLKD ANLRELASDA NFTRDYQDAY KNAHQEMSGR GVGLFGKNIG VLRSWQEIKH
     RVDTKRKLKE EKRVGIGEKI YAGYTGIKRG VLTAIVGKDL RDAYEGNLTS AEWHDFEYND
     PRLRTYSEKL KDDEKAREHE ELQMHINKEA LAAQADILSP EYLARLEKAG RHSDVEYYQE
     LAQRKLIHEV HGRLFEEGEP VMMGDRFMRE KATDSQMRDM IDNAHRKHAE FIDGDRYIRR
     QEHYDIMHEK AQENLEQTYK ELKDHFKRDD IKIEEMPALI AQKVKDTAEG AEIDQKITEE
     LNNFNADVKN YEYSTEVLNK IEDRKQAITD EVNAQIDKIN KYRENAKMQT YVKPIVNEGR
     KLRKLEDHLR NMK