ID   Y147_MYCGE              Reviewed;         375 AA.
AC   P47393;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   31-JAN-2018, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein MG147;
GN   OrderedLocusNames=MG147;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   SEQUENCE REVISION TO 259, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=16407165; DOI=10.1073/pnas.0510013103;
RA   Glass J.I., Assad-Garcia N., Alperovich N., Yooseph S., Lewis M.R.,
RA   Maruf M., Hutchison C.A. III, Smith H.O., Venter J.C.;
RT   "Essential genes of a minimal bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:425-430(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Probably essential, it was not disrupted in a
CC       global transposon mutagenesis study. {ECO:0000269|PubMed:16407165}.
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DR   EMBL; L43967; AAC71365.2; -; Genomic_DNA.
DR   PIR; C64216; C64216.
DR   RefSeq; WP_010869354.1; NC_000908.2.
DR   AlphaFoldDB; P47393; -.
DR   STRING; 243273.MG_147; -.
DR   EnsemblBacteria; AAC71365; AAC71365; MG_147.
DR   KEGG; mge:MG_147; -.
DR   eggNOG; ENOG5031YV4; Bacteria.
DR   HOGENOM; CLU_737345_0_0_14; -.
DR   OMA; QDFFARS; -.
DR   OrthoDB; 1001634at2; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..375
FT                   /note="Uncharacterized protein MG147"
FT                   /id="PRO_0000210442"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   375 AA;  43188 MW;  A14AF77D551BD046 CRC64;
     MLLLRALFLE LKTNKNCKAL LLLLIPLLVG LTLIIYGIVL FSTEGVIDHG DHNHLRARFQ
     LTLEEIIVFV VGSIILFFTL ASFCVSCFML MRSPKQKQLE VDHANKTNLK PKAIVNCDLF
     QLGDYCVFTF KKLSFKQRFK QDFFARSKFS FRSELYRLCL VGVLIALNLA LSLIEIPGIV
     LPWGSSIQFR FFNTAILFIA VRLVGLLSTS LVALITPWLH LLIHPIHTPI SSLFYMVNDF
     LVLWIFYFFF FHLFKAEVIQ TTTVVDNKPF SQLVNTKKTK WTKFFSLLVI SFLCGFIEGL
     GFYFGYFLIL GNVSSLGLKI YYDGLQQRDL INSSNVLFFL MTTTAIFSIK YIFEMLFFFS
     VEKNVVNIAN HFGLY