ID   Y148_TREPA              Reviewed;         192 AA.
AC   O83183;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Uncharacterized protein TP_0148;
GN   OrderedLocusNames=TP_0148;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65140.1; -; Genomic_DNA.
DR   PIR; E71361; E71361.
DR   RefSeq; WP_010881595.1; NC_021490.2.
DR   AlphaFoldDB; O83183; -.
DR   IntAct; O83183; 2.
DR   STRING; 243276.TPANIC_0148; -.
DR   EnsemblBacteria; AAC65140; AAC65140; TP_0148.
DR   KEGG; tpa:TP_0148; -.
DR   eggNOG; ENOG5032PC1; Bacteria.
DR   HOGENOM; CLU_1433901_0_0_12; -.
DR   OrthoDB; 1535489at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..192
FT                   /note="Uncharacterized protein TP_0148"
FT                   /id="PRO_0000202200"
FT   TRANSMEM        5..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  21083 MW;  D85FBDB80F7A89F7 CRC64;
     MVTMVPPLFF VCALFFAEGI GLDRLCIAAL SPRCTLFHTC RFLFLGGILI TGNWVCIHYV
     YDPLALRFLT PLGVGASAFC LSTCSGKLSR TCTSHRAQSE WGLLYALVFY ITYTALNLFE
     ALVMWGVSCV GFLCFSTILR AIHQRITQGN GTAVEKTAAL LLASMGFIAL SLYGTDELWL
     FPIPAAGMRT RL