ID   Y1491_HELPY             Reviewed;         533 AA.
AC   O26024;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Putative phosphate permease HP_1491;
GN   OrderedLocusNames=HP_1491;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Potential transporter for phosphate.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD08533.1; -; Genomic_DNA.
DR   PIR; C64706; C64706.
DR   RefSeq; NP_208282.1; NC_000915.1.
DR   RefSeq; WP_000403632.1; NC_018939.1.
DR   AlphaFoldDB; O26024; -.
DR   SMR; O26024; -.
DR   IntAct; O26024; 3.
DR   STRING; 85962.C694_07725; -.
DR   TCDB; 2.A.20.2.9; the inorganic phosphate transporter (pit) family.
DR   PaxDb; O26024; -.
DR   EnsemblBacteria; AAD08533; AAD08533; HP_1491.
DR   KEGG; hpy:HP_1491; -.
DR   PATRIC; fig|85962.47.peg.1603; -.
DR   eggNOG; COG0306; Bacteria.
DR   OMA; MQAFCIA; -.
DR   PhylomeDB; O26024; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PTHR11101; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphate transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..533
FT                   /note="Putative phosphate permease HP_1491"
FT                   /id="PRO_0000080799"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        129..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        509..529
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   533 AA;  57277 MW;  9B8613D248D56ECC CRC64;
     MEIKNIKEFE KASKKLQKDT LKIALALLFL IGAALLALIF GQANSKGLLL IFAAVIGGYM
     AMNIGANDVS NNVGPAVGSK AISMGGAILI AAICEMLGAI IAGGEVVSTI KGRIVSPEFI
     NDAHIFINVM LASLLSGALW LHVATLIGAP VSTSHSVVGG IMGAGMAAAG MVAVNWHFLS
     GIVASWVISP LMGALIAMFF LMLIKKTIAY KEDKKSAALK VVPYLVALMS LTFSWYLIVK
     VLKRLYALNF EIQLACGCIL ALLIFILFKR FVLKKAPQLE NSHESINELF NVPLIFAAAL
     LSFAHGANDV ANAIGPLAAI SQTLEDANSP IGNTLSSVPL WIMVVGAAGI ALGLSLYGPK
     LIKTVGSEIT ELDKMQAFCI ALSAVITVLL ASQLGLPVSS THIVVGAVFG VGFLRERLRE
     QSRRRFARIR DNIVAAHFGE DLEEIEGFLE RFDKANLKEK SLMLESLKKS KNTAIALELK
     KKEKKSLKKV YKEEVIKRSI LKKIVTAWLV TVPVSALLGA LLFVALGFIE KYF