ID   Y1491_MYCTO             Reviewed;         252 AA.
AC   P9WFS2; L0T706; P67117; P71772;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=TVP38/TMEM64 family membrane protein MT1538;
GN   OrderedLocusNames=MT1538;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45805.1; -; Genomic_DNA.
DR   PIR; F70711; F70711.
DR   RefSeq; WP_003407583.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WFS2; -.
DR   EnsemblBacteria; AAK45805; AAK45805; MT1538.
DR   GeneID; 45425471; -.
DR   KEGG; mtc:MT1538; -.
DR   PATRIC; fig|83331.31.peg.1655; -.
DR   HOGENOM; CLU_038944_4_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032816; SNARE_assoc.
DR   InterPro; IPR015414; TMEM64.
DR   PANTHER; PTHR12677; PTHR12677; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..252
FT                   /note="TVP38/TMEM64 family membrane protein MT1538"
FT                   /id="PRO_0000428487"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   252 AA;  26576 MW;  3E63BE13217B8201 CRC64;
     MTAPAICNTT ETVHGIATSL GAVARQASLP RIVGTVVGIT VLVVVALLVP VPTAVELRDW
     AKSLGAWFPL AFLLVHTVVT VPPFPRTAFT LAAGLLFGSV VGVFIAVVGS TASAVIAMLL
     VRATGWQLNS LVRRRAINRL DERLRERGWL AILSLRLIPV VPFAAINYAA GASGVRILSF
     AWATLAGLLP GTAAVVILGD AFAGSGSPLL ILVSVCTGAL GLTGLVYEIR NYRRQHRRMP
     GYDDPVREPA LI