ID   Y1491_MYCTU             Reviewed;         252 AA.
AC   P9WFS3; L0T706; P67117; P71772;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=TVP38/TMEM64 family membrane protein Rv1491c;
GN   OrderedLocusNames=Rv1491c; ORFNames=MTCY277.13c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TVP38/TMEM64 family. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44252.1; -; Genomic_DNA.
DR   PIR; F70711; F70711.
DR   RefSeq; NP_216007.1; NC_000962.3.
DR   RefSeq; WP_003407583.1; NZ_NVQJ01000004.1.
DR   AlphaFoldDB; P9WFS3; -.
DR   STRING; 83332.Rv1491c; -.
DR   PaxDb; P9WFS3; -.
DR   DNASU; 886513; -.
DR   GeneID; 45425471; -.
DR   GeneID; 886513; -.
DR   KEGG; mtu:Rv1491c; -.
DR   TubercuList; Rv1491c; -.
DR   eggNOG; COG0398; Bacteria.
DR   OMA; VGPWFPL; -.
DR   PhylomeDB; P9WFS3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR032816; SNARE_assoc.
DR   InterPro; IPR015414; TMEM64.
DR   PANTHER; PTHR12677; PTHR12677; 1.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..252
FT                   /note="TVP38/TMEM64 family membrane protein Rv1491c"
FT                   /id="PRO_0000198638"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   252 AA;  26576 MW;  3E63BE13217B8201 CRC64;
     MTAPAICNTT ETVHGIATSL GAVARQASLP RIVGTVVGIT VLVVVALLVP VPTAVELRDW
     AKSLGAWFPL AFLLVHTVVT VPPFPRTAFT LAAGLLFGSV VGVFIAVVGS TASAVIAMLL
     VRATGWQLNS LVRRRAINRL DERLRERGWL AILSLRLIPV VPFAAINYAA GASGVRILSF
     AWATLAGLLP GTAAVVILGD AFAGSGSPLL ILVSVCTGAL GLTGLVYEIR NYRRQHRRMP
     GYDDPVREPA LI