ID   Y1493_THEPD             Reviewed;         228 AA.
AC   A1S0B0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=UPF0173 metal-dependent hydrolase Tpen_1493 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=Tpen_1493;
OS   Thermofilum pendens (strain DSM 2475 / Hrk 5).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermofilales; Thermofilaceae;
OC   Thermofilum.
OX   NCBI_TaxID=368408;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2475 / Hrk 5;
RX   PubMed=18263724; DOI=10.1128/jb.01949-07;
RA   Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E.,
RA   Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M.,
RA   Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B.,
RA   Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N.;
RT   "Genome sequence of Thermofilum pendens reveals an exceptional loss of
RT   biosynthetic pathways without genome reduction.";
RL   J. Bacteriol. 190:2957-2965(2008).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; CP000505; ABL78890.1; -; Genomic_DNA.
DR   RefSeq; WP_011753155.1; NC_008698.1.
DR   AlphaFoldDB; A1S0B0; -.
DR   SMR; A1S0B0; -.
DR   STRING; 368408.Tpen_1493; -.
DR   EnsemblBacteria; ABL78890; ABL78890; Tpen_1493.
DR   GeneID; 4601402; -.
DR   KEGG; tpe:Tpen_1493; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   Proteomes; UP000000641; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..228
FT                   /note="UPF0173 metal-dependent hydrolase Tpen_1493"
FT                   /id="PRO_1000013516"
SQ   SEQUENCE   228 AA;  24794 MW;  B792C947CEF5AB5E CRC64;
     MARLRYLGHA AFDVELEGFD GRKRRILLDP WLENPLSPVK PSDYRGARVD YIFVTHDHGD
     HLGNAVELAR ATGAKVVAVY ELAEELSKEG VQAVGANIGG PLALEGIQAV FTPALHSSSK
     GAPTGVVVRG RDTAVYHAGD TGLFGDMRLI GELYAPDVAL LPIGGHFTMG VVEALKAVEL
     LRPRLAIPMH YNTFPEIRAD PEKFKELVEA TTRTKVVVLK PGDYVEYP