ID   Y1496_PYRFU             Reviewed;         338 AA.
AC   Q8U0T6;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=UPF0252 protein PF1496;
GN   OrderedLocusNames=PF1496;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0252 family. {ECO:0000305}.
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DR   EMBL; AE009950; AAL81620.1; -; Genomic_DNA.
DR   RefSeq; WP_011012643.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U0T6; -.
DR   SMR; Q8U0T6; -.
DR   STRING; 186497.PF1496; -.
DR   PRIDE; Q8U0T6; -.
DR   EnsemblBacteria; AAL81620; AAL81620; PF1496.
DR   GeneID; 41713311; -.
DR   KEGG; pfu:PF1496; -.
DR   PATRIC; fig|186497.12.peg.1559; -.
DR   eggNOG; arCOG07144; Archaea.
DR   HOGENOM; CLU_788987_0_0_2; -.
DR   OMA; VYIVHTV; -.
DR   OrthoDB; 62980at2157; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007562; Transglutaminase-like_domain.
DR   Pfam; PF04473; DUF553; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..338
FT                   /note="UPF0252 protein PF1496"
FT                   /id="PRO_0000159559"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   338 AA;  39907 MW;  7036385E96EC7C0D CRC64;
     MKELDQILEK CAEEIDPLSH EIAERIRKLK NLPKDEMFLE YLRIIDFTST TKIPWRKKNY
     ILIILWKYGE KIERLLYSRL EHFGRANVPK RYFRLVDGKI LSMLFLVFIL FPAFTSHIWS
     FRLGYEEIQV GKEITFNENL CEYRTAWLYD FKASMVCTIK YGYGKVNIRL NSTNPMEAGV
     EVQRFISQIP YDYARLESGF SYIQTPRETI GRRIGVCSDF AILTAQVLLD NNVSPVYIIH
     TLFKGDITGG HATAALFING TLWIFDWGSA PVTFSEYLDT IDRLWEVREV RVYRLTESSI
     VLDRVYKGEP ESDAWRYVYT LTMLIGIFII KRREWLWI