ID   Y1497_NEIMB             Reviewed;         921 AA.
AC   Q7DDB6;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Probable TonB-dependent receptor NMB1497;
DE   Flags: Precursor;
GN   OrderedLocusNames=NMB1497;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17038831; DOI=10.4161/hv.1.2.1651;
RA   Vipond C., Wheeler J.X., Jones C., Feavers I.M., Suker J.;
RT   "Characterization of the protein content of a meningococcal outer membrane
RT   vesicle vaccine by polyacrylamide gel electrophoresis and mass
RT   spectrometry.";
RL   Hum. Vaccin. 1:80-84(2005).
CC   -!- FUNCTION: Probable receptor, TonB-dependent. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Present in outer membrane vesicle formulations which are
CC       used as vaccines in human.
CC   -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE002098; AAF41853.1; -; Genomic_DNA.
DR   RefSeq; NP_274505.1; NC_003112.2.
DR   RefSeq; WP_002244190.1; NC_003112.2.
DR   AlphaFoldDB; Q7DDB6; -.
DR   STRING; 122586.NMB1497; -.
DR   TCDB; 1.B.14.7.2; the outer membrane receptor (omr) family.
DR   PaxDb; Q7DDB6; -.
DR   PRIDE; Q7DDB6; -.
DR   EnsemblBacteria; AAF41853; AAF41853; NMB1497.
DR   KEGG; nme:NMB1497; -.
DR   PATRIC; fig|122586.8.peg.1893; -.
DR   HOGENOM; CLU_008287_19_1_4; -.
DR   OMA; QVNIRGM; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031230; C:intrinsic component of cell outer membrane; IBA:GO_Central.
DR   GO; GO:0015344; F:siderophore uptake transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR   GO; GO:0044718; P:siderophore transmembrane transport; IBA:GO_Central.
DR   Gene3D; 2.170.130.10; -; 1.
DR   Gene3D; 2.40.170.20; -; 1.
DR   InterPro; IPR039426; BtuB-like.
DR   InterPro; IPR012910; Plug_dom.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR   InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR   InterPro; IPR010917; TonB_rcpt_CS.
DR   PANTHER; PTHR30069; PTHR30069; 1.
DR   Pfam; PF07715; Plug; 1.
DR   Pfam; PF00593; TonB_dep_Rec; 1.
DR   PROSITE; PS01156; TONB_DEPENDENT_REC_2; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Membrane; Receptor; Reference proteome; Signal;
KW   TonB box; Transmembrane; Transmembrane beta strand.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..921
FT                   /note="Probable TonB-dependent receptor NMB1497"
FT                   /id="PRO_0000320273"
FT   MOTIF           904..921
FT                   /note="TonB C-terminal box"
SQ   SEQUENCE   921 AA;  104222 MW;  67985B75EDF8819D CRC64;
     MRSSFRLKPI CFYLMGVTLY HYSYAEDAGR AGSEAQIQVL EDVHVKAKRV PKDKKVFTDA
     RAVSTRQDIF KSSENLDNIV RSIPGAFTQQ DKSSGIVSLN IRGDSGFGRV NTMVDGITQT
     FYSTSTDAGR AGGSSQFGAS VDSNFIAGLD VVKGSFSGSA GINSLAGSAN LRTLGVDDVV
     QGNNTYGLLL KGLTGTNSTK GNAMAAIGAR KWLESGASVG VLYGHSRRSV AQNYRVGGGG
     QHIGNFGAEY LERRKQRYFV QEGALKFNSD SGKWERDLQR QQWKYKPYKN YNNQELQKYI
     EEHDKSWREN LAPQYDITPI DPSSLKQQSA GNLFKLEYDG VFNKYTAQFR DLNTKIGSRK
     IINRNYQFNY GLSLNPYTNL NLTAAYNSGR QKYPKGSKFT GWGLLKDFET YNNAKILDLN
     NTATFRLPRE TELQTTLGFN YFHNEYGKNR FPEELGLFFD GPDQDNGLYS YLGRFKGDKG
     LLPQKSTIVQ PAGSQYFNTF YFDAALKKDI YRLNYSTNTV GYRFGGEYTG YYGSDDEFKR
     AFGENSPTYK KHCNRSCGIY EPVLKKYGKK RANNHSVSIS ADFGDYFMPF ASYSRTHRMP
     NIQEMYFSQI GDSGVHTALK PERANTWQFG FNTYKKGLLK QDDTLGLKLV GYRSRIDNYI
     HNVYGKWWDL NGDIPSWVSS TGLAYTIQHR NFKDKVHKHG FELELNYDYG RFFTNLSYAY
     QKSTQPTNFS DASESPNNAS KEDQLKQGYG LSRVSALPRD YGRLEVGTRW LGNKLTLGGA
     MRYFGKSIRA TAEERYIDGT NGGNTSNFRQ LGKRSIKQTE TLARQPLIFD FYAAYEPKKN
     LIFRAEVKNL FDRRYIDPLD AGNDAATQRY YSSFDPKDKD EDVTCNADKT LCNGKYGGTS
     KSVLTNFARG RTFLMTMSYK F